[HTML][HTML] RIG-I-like receptors: their regulation and roles in RNA sensing
J Rehwinkel, MU Gack - Nature Reviews Immunology, 2020 - nature.com
Retinoic acid-inducible gene I (RIG-I)-like receptors (RLRs) are key sensors of virus
infection, mediating the transcriptional induction of type I interferons and other genes that …
infection, mediating the transcriptional induction of type I interferons and other genes that …
An overview of autophagy: Mechanism, regulation and research progress
W Cao, J Li, K Yang, D Cao - Bulletin du cancer, 2021 - Elsevier
Autophagy refers to the formation of autophagosomes by membrane wrapping part of the
cytoplasm and the organelles and proteins that need to be degraded in the cells …
cytoplasm and the organelles and proteins that need to be degraded in the cells …
[HTML][HTML] The role of autophagy in viral infections
T Chen, S Tu, L Ding, M Jin, H Chen, H Zhou - Journal of biomedical …, 2023 - Springer
Autophagy is an evolutionarily conserved catabolic cellular process that exerts antiviral
functions during a viral invasion. However, co-evolution and co-adaptation between viruses …
functions during a viral invasion. However, co-evolution and co-adaptation between viruses …
[HTML][HTML] Autophagy and macrophage functions: inflammatory response and phagocytosis
MY Wu, JH Lu - Cells, 2019 - mdpi.com
Autophagy is a conserved bulk degradation and recycling process that plays important roles
in multiple biological functions, including inflammatory responses. As an important …
in multiple biological functions, including inflammatory responses. As an important …
[HTML][HTML] A comprehensive review on cancer vaccines and vaccine strategies in hepatocellular carcinoma
HCC, the most prevalent form of primary liver cancer, presents a substantial global health
challenge due to its high mortality and limited therapeutic options. This review delves into …
challenge due to its high mortality and limited therapeutic options. This review delves into …
Coronavirus disease 2019 (COVID‐19) update: From metabolic reprogramming to immunometabolism
M Rudiansyah, SA Jasim… - Journal of Medical …, 2022 - Wiley Online Library
The field of immunometabolism investigates and describes the effects of metabolic rewiring
in immune cells throughout activation and the fates of these cells. Recently, it has been …
in immune cells throughout activation and the fates of these cells. Recently, it has been …
[HTML][HTML] MDA5 RNA-sensing pathway activation by Mycobacterium tuberculosis promotes innate immune subversion and pathogen survival
Host cytosolic sensing of Mycobacterium tuberculosis (M. tuberculosis) RNA by the RIG-I–
like receptor (RLR) family perturbs innate immune control within macrophages; however, a …
like receptor (RLR) family perturbs innate immune control within macrophages; however, a …
[HTML][HTML] The evolving role of TRAFs in mediating inflammatory responses
B Dhillon, F Aleithan, Z Abdul-Sater… - Frontiers in …, 2019 - frontiersin.org
TRAFs [tumor necrosis factor (TNF) receptor associated factors] are a family of signaling
molecules that function downstream of multiple receptor signaling pathways and play a …
molecules that function downstream of multiple receptor signaling pathways and play a …
[HTML][HTML] Pharmacological induction of autophagy reduces inflammation in macrophages by degrading immunoproteasome subunits
J Zhou, C Li, M Lu, G Jiang, S Chen, H Li, K Lu - Plos Biology, 2024 - journals.plos.org
Defective autophagy is linked to proinflammatory diseases. However, the mechanisms by
which autophagy limits inflammation remain elusive. Here, we found that the pan-FGFR …
which autophagy limits inflammation remain elusive. Here, we found that the pan-FGFR …
[HTML][HTML] Mechanisms of TLR4-mediated autophagy and nitroxidative stress
K Zhang, Q Huang, S Deng, Y Yang, J Li… - Frontiers in Cellular and …, 2021 - frontiersin.org
Pathogenic infections have badly affected public health and the development of the
breeding industry. Billions of dollars are spent every year fighting against these pathogens …
breeding industry. Billions of dollars are spent every year fighting against these pathogens …