Lipids and lipid derivatives for RNA delivery

Y Zhang, C Sun, C Wang, KE Jankovic… - Chemical reviews, 2021 - ACS Publications
RNA-based therapeutics have shown great promise in treating a broad spectrum of
diseases through various mechanisms including knockdown of pathological genes …

Biointerfacing and applications of cell membrane-coated nanoparticles

AV Kroll, RH Fang, L Zhang - Bioconjugate chemistry, 2017 - ACS Publications
The cell membrane-coated nanoparticle is a biomimetic platform consisting of a
nanoparticulate core coated with membrane derived from a cell, such as a red blood cell …

Cancer cell membrane-coated adjuvant nanoparticles with mannose modification for effective anticancer vaccination

R Yang, J Xu, L Xu, X Sun, Q Chen, Y Zhao, R Peng… - ACS …, 2018 - ACS Publications
Tumor vaccines for cancer prevention and treatment have attracted tremendous interests in
the area of cancer immunotherapy in recent years. In this work, we present a strategy to …

Fc‐fusion proteins: new developments and future perspectives

DM Czajkowsky, J Hu, Z Shao… - EMBO molecular medicine, 2012 - embopress.org
Since the first description in 1989 of CD4‐Fc‐fusion antagonists that inhibit human immune
deficiency virus entry into T cells, Fc‐fusion proteins have been intensely investigated for …

Core–shell-type lipid–polymer hybrid nanoparticles as a drug delivery platform

B Mandal, H Bhattacharjee, N Mittal, H Sah… - … , Biology and Medicine, 2013 - Elsevier
The focus of nanoparticle design over the years has evolved toward more complex
nanoscopic core–shell architecture using a single delivery system to combine multiple …

Cytokines as biomarkers of nanoparticle immunotoxicity

M Elsabahy, KL Wooley - Chemical Society Reviews, 2013 - pubs.rsc.org
Nanoscale objects, whether of biologic origin or synthetically created, are being developed
into devices for a variety of bionanotechnology diagnostic and pharmaceutical applications …

Engineering nano‐and microparticles to tune immunity

JJ Moon, B Huang, DJ Irvine - Advanced materials, 2012 - Wiley Online Library
The immune system can be a cure or cause of disease, fulfilling a protective role in attacking
cancer or pathogenic microbes but also causing tissue destruction in autoimmune disorders …

[HTML][HTML] Exploitation of the macrophage mannose receptor (CD206) in infectious disease diagnostics and therapeutics

AK Azad, MVS Rajaram… - Journal of cytology & …, 2014 - ncbi.nlm.nih.gov
The macrophage mannose receptor (MR, CD206) is a C-type lectin expressed
predominantly by most tissue macrophages, dendritic cells and specific lymphatic or …

Glycopolymer probes of signal transduction

LL Kiessling, JC Grim - Chemical Society Reviews, 2013 - pubs.rsc.org
Glycans are key participants in biological processes ranging from reproduction to cellular
communication to infection. Revealing glycan roles and the underlying molecular …

Interactions between nanoparticles and dendritic cells: from the perspective of cancer immunotherapy

J Jia, Y Zhang, Y Xin, C Jiang, B Yan, S Zhai - Frontiers in oncology, 2018 - frontiersin.org
Dendritic cells (DCs) are the primary antigen-presenting cells and play key roles in the
orchestration of the innate and adaptive immune system. Targeting DCs by nanotechnology …