Exosomes: Large-scale production, isolation, drug loading efficiency, and biodistribution and uptake
I Kimiz-Gebologlu, SS Oncel - Journal of Controlled Release, 2022 - Elsevier
Exosomes are nanovesicles with different contents that play a role in various biological and
pathological processes. It offers significant advantages over other delivery systems such as …
pathological processes. It offers significant advantages over other delivery systems such as …
Review on strategies and technologies for exosome isolation and purification
J Chen, P Li, T Zhang, Z Xu, X Huang… - … in bioengineering and …, 2022 - frontiersin.org
Exosomes, a nano-sized subtype of extracellular vesicles secreted from almost all living
cells, are capable of transferring cell-specific constituents of the source cell to the recipient …
cells, are capable of transferring cell-specific constituents of the source cell to the recipient …
Cell death, therapeutics, and the immune response in cancer
Induction of cell death is inexorably linked with cancer therapy, but this can also initiate
wound-healing processes that have been linked to cancer progression and therapeutic …
wound-healing processes that have been linked to cancer progression and therapeutic …
Extracellular vesicles as tools and targets in therapy for diseases
Extracellular vesicles (EVs) are nano-sized, membranous structures secreted into the
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
extracellular space. They exhibit diverse sizes, contents, and surface markers and are …
Engineering extracellular vesicles as delivery systems in therapeutic applications
L Wang, D Wang, Z Ye, J Xu - Advanced Science, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are transport vesicles secreted by living cells and released into
the extracellular environment. Recent studies have shown that EVs serve as “messengers” …
the extracellular environment. Recent studies have shown that EVs serve as “messengers” …
Principles and problems of exosome isolation from biological fluids
EI Yakubovich, AG Polischouk… - … ), Supplement Series A …, 2022 - Springer
Exosomes, the subclass of small membrane extracellular vesicles, have great diagnostic
and therapeutic potential, but the lack of standardized methods for their efficient isolation …
and therapeutic potential, but the lack of standardized methods for their efficient isolation …
[HTML][HTML] Breakthrough of extracellular vesicles in pathogenesis, diagnosis and treatment of osteoarthritis
Z Liu, Y Zhuang, L Fang, C Yuan, X Wang, K Lin - Bioactive Materials, 2023 - Elsevier
Osteoarthritis (OA) is a highly prevalent whole-joint disease that causes disability and pain
and affects a patient's quality of life. However, currently, there is a lack of effective early …
and affects a patient's quality of life. However, currently, there is a lack of effective early …
Bioinspired engineering of fusogen and targeting moiety equipped nanovesicles
Cell-derived small extracellular vesicles have been exploited as potent drug vehicles.
However, significant challenges hamper their clinical translation, including inefficient …
However, significant challenges hamper their clinical translation, including inefficient …
[HTML][HTML] Cell-derived nanovesicles prepared by membrane extrusion are good substitutes for natural extracellular vesicles
Extracellular vesicles (EV) as drug delivery nanocarriers are under intense investigation.
Although clinical-grade EVs have been produced on a large-scale, low yield and high …
Although clinical-grade EVs have been produced on a large-scale, low yield and high …
Dual-aptamer-assisted and logic gate for cyclic enzymatic signal amplification electrochemical detection of tumor-derived small extracellular vesicles
Y Yu, Q Guo, W Jiang, H Zhang, C Cai - Analytical Chemistry, 2021 - ACS Publications
Small extracellular vesicles (sEVs), often referred to as exosomes, are potential biomarkers
for noninvasive cancer diagnosis. However, because of their phenotype heterogeneity …
for noninvasive cancer diagnosis. However, because of their phenotype heterogeneity …