In the early 1900s, numerous seminal publications reported that high rates of cancer
occurred in certain occupations. During this period, work with infectious agents produced …

The lentivirus human immunodeficiency virus (HIV) causes AIDS by interacting with a large
number of different cells in the body and escaping the host immune response against it. HIV …

We constructed an infectious molecular clone of acquired immunodeficiency syndrome-
associated retrovirus. Upon transfection, this clone directed the production of infectious virus …

Acquired immune deficiency syndrome (AIDS) is characterized by opportunistic infections
and by 'opportunistic neoplasms'(for example, Kaposi's sarcoma) 1. Persistent generalized …

Established for 20 years as the definitive virology reference, the two-volume classic Fields
Virology is in its thoroughly revised, updated Fifth Edition. More than 100 world-renowned …

Many viruses, including retroviruses, are characterized by their specific cell tropism1–3.
Lymphadenopathy-associated virus (LAV) is a human lymphotropic retrovirus isolated from …

One of the common neurological complications in patients with the acquired immune
deficiency syndrome (AIDS) is a subacute encephalopathy with progressive dementia. By …

Cells with properties characteristic of mononuclear phagocytes were evaluated for infectivity
with five different isolates of the AIDS virus, HTLV-III/LAV. Mononuclear phagocytes cultured …

The human T-cell lines MT-2 and MT-4 carry the human T-cell leukemia virus type I (HTLV-I).
When MT-2 and MT-4 were infected with HTLV-III, the probable etiologic agent of the …

In a 6-week clinical trial 4 dose regimens of 3'-azido-3'-deoxythymidine (AZT), a thymidine
analogue with potent anti-viral activity against HTLV-III in vitro, were examined in 19 patients …