Answer questions and earn CME/CNE The management of squamous cell carcinomas of
the anal canal has evolved from surgery as first‐line treatment to curative chemoradiation …

Background Squamous cell carcinoma of the anal canal (SCCA) is a rare malignancy
associated with infection by human papillomavirus (HPV). No consensus treatment …

Tumors of the anus and perianal skin are rare. Their presentation can vary and often mimics
common benign anal pathology, thereby delaying diagnosis and appropriate and timely …

The NCCN Guidelines for Anal Carcinoma provide recommendations for the management of
patients with squamous cell carcinoma of the anal canal or perianal region. Primary …

The second factor that has resulted in a paradigm shift in understanding the etiology of anal
cancer is the discovery that the human papilloma virus (HPV), especially HPV serotypes 16 …

increase in incidence, especially in immunosuppressed patients. 6, 11–16 Although various
tumors can arise in the anal canal and perianal region, this practice parameter will focus …

BACKGROUND: Only 4 prospective randomized phase 3 trials have been reported for anal
cancer. A prognostic factor analysis for anal cancer from a prospective database has been …

Although rare, the rate of squamous cell carcinoma of the anus (SCCA) is rising globally.
Most patients present with nonmetastatic disease and are curable with appropriate …

Purpose The long-term update of US GI Intergroup RTOG 98-11 anal cancer trial found that
concurrent chemoradiation (CCRT) with fluorouracil (5-FU) plus mitomycin had a significant …

Squamous cell carcinoma of the anal canal (SCCA) is a rare gastrointestinal malignancy
with an increasing annual incidence globally. The majority of cases are linked to prior …