Humoral responses and serological assays in SARS-CoV-2 infections

Y Galipeau, M Greig, G Liu, M Driedger… - Frontiers in …, 2020 - frontiersin.org
In December 2019, the novel betacoronavirus Severe Acute Respiratory Disease
Coronavirus 2 (SARS-CoV-2) was first detected in Wuhan, China. SARS-CoV-2 has since …

A comprehensive review about the molecular structure of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2): Insights into natural products against …

EM Saied, YA El-Maradny, AA Osman, AMG Darwish… - Pharmaceutics, 2021 - mdpi.com
In 2019, the world suffered from the emergence of COVID-19 infection, one of the most
difficult pandemics in recent history. Millions of confirmed deaths from this pandemic have …

Sensitivity of infectious SARS-CoV-2 B. 1.1. 7 and B. 1.351 variants to neutralizing antibodies

D Planas, T Bruel, L Grzelak, F Guivel-Benhassine… - Nature medicine, 2021 - nature.com
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) B. 1.1. 7 and B. 1.351
variants were first identified in the United Kingdom and South Africa, respectively, and have …

IgA dominates the early neutralizing antibody response to SARS-CoV-2

D Sterlin, A Mathian, M Miyara, A Mohr… - Science translational …, 2021 - science.org
Humoral immune responses are typically characterized by primary IgM antibody responses
followed by secondary antibody responses associated with immune memory and composed …

Rapid generation of durable B cell memory to SARS-CoV-2 spike and nucleocapsid proteins in COVID-19 and convalescence

GE Hartley, ESJ Edwards, PM Aui, N Varese… - Science …, 2020 - science.org
Lasting immunity following SARS-CoV-2 infection is questioned because serum antibodies
decline in convalescence. However, functional immunity is mediated by long-lived memory T …

Syncytia formation by SARS‐CoV‐2‐infected cells

J Buchrieser, J Dufloo, M Hubert, B Monel… - The EMBO …, 2020 - embopress.org
Severe cases of COVID‐19 are associated with extensive lung damage and the presence of
infected multinucleated syncytial pneumocytes. The viral and cellular mechanisms …

High prevalence of SARS-CoV-2 antibodies in pets from COVID-19+ households

M Fritz, B Rosolen, E Krafft, P Becquart, E Elguero… - One Health, 2020 - Elsevier
In a survey of household cats and dogs of laboratory-confirmed COVID-19 patients, we
found a high seroprevalence of SARS-CoV-2 antibodies, ranging from 21% to 53 …

Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection

N Smith, P Goncalves, B Charbit, L Grzelak… - Nature …, 2021 - nature.com
Coordinated local mucosal and systemic immune responses following severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) infection either protect against …

[HTML][HTML] Antibody persistence in the first 6 months following SARS-CoV-2 infection among hospital workers: a prospective longitudinal study

AG L'Huillier, B Meyer, DO Andrey, I Arm-Vernez… - Clinical Microbiology …, 2021 - Elsevier
Objectives To evaluate longitudinally the persistence of humoral immunity for up to 6 months
in a cohort of hospital employees with mild coronavirus disease 2019 (COVID-19). Methods …

[HTML][HTML] Intranasal vaccination with a lentiviral vector protects against SARS-CoV-2 in preclinical animal models

MW Ku, M Bourgine, P Authié, J Lopez, K Nemirov… - Cell host & …, 2021 - cell.com
To develop a vaccine candidate against coronavirus disease 2019 (COVID-19), we
generated a lentiviral vector (LV) eliciting neutralizing antibodies against the Spike …