Background The UK government reclassified gabapentin and pregabalin as 'controlled
drugs' from April 2019. This study aimed to describe the trends in gabapentinoid prescribing …

Huoxuezhitong capsule (HXZT, activating blood circulation and relieving pain capsule), has
been applied for osteoarthritis since 1974. It consists of Angelica sinensis (Oliv.) Diels …

Variable inflammatory and neuropathic components and spatiotemporal evolution underlie
the heterogeneity of osteoarthritis pain phenotypes, which must be considered to adequately …

Objective Despite the prevalence of osteoarthritis (OA) in England, few studies have
examined the health economic impact of chronic pain associated with OA. The aim of this …

Background Unlicensed medicines are used across the UK to treat an individual's clinical
needs when there are no appropriate licensed alternatives. Patients, carers and parents …

Background Analgesics prescriptions may provide a marker for identifying individuals at
higher risk of suicide. In particular, awareness of which analgesics are implicated may help …

Objective Pharmacotherapy is the most common strategies to reduce pain for osteoarthritis
(OA) patients. To analyze the trend and pattern of prescription analgesic medication use in …

Aims This study aimed to investigate the prescribing trajectory, geographical variation and
population factors, including socioeconomic status (SES), related to prescribing …

Objective Gabapentin can treat neuropathic pain syndromes and has increasingly been
prescribed to treat nociplastic pain. Some patients with knee osteoarthritis (OA) suffer from …

Purpose Osteoarthritis (OA) is a chronic painful condition that often affects large joints such
as the knee. Treatment guidelines recommend paracetamol, nonsteroidal anti‐inflammatory …