Decoding human cytomegalovirus for the development of innovative diagnostics to detect congenital infection
Cytomegalovirus is the most common cause of congenital infectious disease and the
leading nongenetic etiology of sensorineural hearing loss. Although most infected neonates …
leading nongenetic etiology of sensorineural hearing loss. Although most infected neonates …
[HTML][HTML] Understanding the Cytomegalovirus Cyclin-Dependent Kinase Ortholog pUL97 as a Multifaceted Regulator and an Antiviral Drug Target
M Marschall, M Schütz, M Wild, E Socher, C Wangen… - Cells, 2024 - mdpi.com
Herpesviral protein kinases, such as the therapy-relevant pUL97 of human cytomegalovirus
(HCMV), are important for viral replication efficiency as well as pathogenesis, and represent …
(HCMV), are important for viral replication efficiency as well as pathogenesis, and represent …
Apelin, APJ, and ELABELA: role in placental function, pregnancy, and foetal development—an overview
M Dawid, E Mlyczyńska, M Jurek, N Respekta, K Pich… - Cells, 2021 - mdpi.com
The apelinergic system, which includes the apelin receptor (APJ) as well as its two specific
ligands, namely apelin and ELABELA (ELA/APELA/Toddler), have been the subject of many …
ligands, namely apelin and ELABELA (ELA/APELA/Toddler), have been the subject of many …
[HTML][HTML] Central role of the placenta during viral infection: Immuno-competences and miRNA defensive responses
V Zaga-Clavellina, L Diaz, A Olmos-Ortiz… - … et Biophysica Acta (BBA …, 2021 - Elsevier
Pregnancy is a unique immunological condition in which an “immune-diplomatic” dialogue
between trophoblasts and maternal immune cells is established to protect the fetus from …
between trophoblasts and maternal immune cells is established to protect the fetus from …
Host-viral interactions at the maternal-fetal interface. What we know and what we need to know
JH Girsch, MC Mejia Plazas, A Olivier, M Farah… - Frontiers in …, 2022 - frontiersin.org
In humans, the hemochorial placenta is a unique temporary organ that forms during
pregnancy to support fetal development, gaseous exchange, delivery of nutrition, removal of …
pregnancy to support fetal development, gaseous exchange, delivery of nutrition, removal of …
Suppression of human trophoblast syncytialization by human cytomegalovirus infection
N Mimura, T Nagamatsu, K Morita, A Taguchi, T Toya… - Placenta, 2022 - Elsevier
Introduction Placental dysfunction triggers fetal growth restriction in congenital human
cytomegalovirus (HCMV) infection. Studies suggest that HCMV infection interferes with the …
cytomegalovirus (HCMV) infection. Studies suggest that HCMV infection interferes with the …
Dipeptidyl peptidase IV inhibition delays developmental programming of obesity and metabolic disease in male offspring of obese mothers
KRC Montaniel, M Bucher, EA Phillips, C Li… - … origins of health and …, 2022 - cambridge.org
Maternal obesity programs the offspring to metabolic diseases later in life; however, the
mechanisms of programming are yet unclear, and no strategies exist for addressing its …
mechanisms of programming are yet unclear, and no strategies exist for addressing its …
Endothelial cell infection by Guinea pig cytomegalovirus is a lytic or persistent infection depending on tissue origin but requires viral pentamer complex and pp65 …
KY Choi, N El-Hamdi, A McGregor - Journal of Virology, 2022 - Am Soc Microbiol
The guinea pig is the only small animal model for congenital cytomegalovirus (CMV) but
requires species-specific guinea pig cytomegalovirus (GPCMV). Infection of epithelial cells …
requires species-specific guinea pig cytomegalovirus (GPCMV). Infection of epithelial cells …
Single-nucleus RNA sequencing reveals distinct pathophysiological trophoblast signatures in spontaneous preterm birth subtypes
C Uhm, J Gu, W Ju, S Pizzella, H Oktay, JYC Peng… - Cell & Bioscience, 2025 - Springer
Spontaneous preterm birth (sPTB) poses significant challenges, affecting neonatal health
and neurodevelopmental outcomes worldwide. The specific effects of placental trophoblasts …
and neurodevelopmental outcomes worldwide. The specific effects of placental trophoblasts …
[HTML][HTML] 影响山羊产羔数lncRNA 的筛选及功能分析
李耀坤, 许香萍, 陆婷婷, 练志全, 邹娴, 赵智锋… - 畜牧兽医学报, 2020 - html.rhhz.net
旨在分析高, 低繁殖力川中黑山羊卵巢组织中长链非编码RNA (long non-coding RNA, lncRNA)
的表达谱, 探讨lncRNA 与山羊生殖调控的关系, 为解释lncRNA 在山羊繁殖调控中的分子机制 …
的表达谱, 探讨lncRNA 与山羊生殖调控的关系, 为解释lncRNA 在山羊繁殖调控中的分子机制 …