RET tyrosine kinase signaling in development and cancer

E Arighi, MG Borrello, H Sariola - Cytokine & growth factor reviews, 2005 - Elsevier
The variety of diseases caused by mutations in RET receptor tyrosine kinase provides a
classic example of phenotypic heterogeneity. Gain-of-function mutations of RET are …

Medullary and papillary carcinoma of the thyroid gland occurring as a collision tumour: report of three cases with molecular analysis and review of the literature

S Rossi, L Fugazzola, L De Pasquale… - Endocrine-Related …, 2005 - erc.bioscientifica.com
We report the simultaneous occurrence of medullary thyroid carcinoma (MTC) and papillary
thyroid carcinoma (PTC), presenting as spatially distinct and well-defined tumour …

Concurrent occurrence of medullary thyroid carcinoma and papillary thyroid carcinoma in the same thyroid should be considered as coincidental

WG Kim, G Gong, EY Kim, TY Kim, SJ Hong… - Clinical …, 2010 - Wiley Online Library
Objectives The simultaneous occurrence of medullary thyroid carcinoma (MTC) and
papillary thyroid carcinoma (PTC) in the same thyroid gland is documented. In this study, we …

RET receptor signaling: dysfunction in thyroid cancer and Hirschsprung's disease

N Asai, M Jijiwa, A Enomoto, K Kawai… - Pathology …, 2006 - Wiley Online Library
Gain‐of‐function mutations within the receptor tyrosine kinase gene RET cause inherited
and non‐inherited thyroid cancer. Somatic gene rearrangements of RET have been found in …

Collision tumors of the thyroid: A case report and review of the literature

N Ryan, G Walkden, D Lazic, P Tierney - Head & Neck, 2015 - Wiley Online Library
Background Collision tumors of the thyroid are a rare pathology that present a diagnostic
and treatment challenge. In this report, we present an interesting case and a review of the …

Primary spindle cell lesions of the thyroid gland: an overview

G Papi, S Corrado, VA LiVolsi - Pathology Patterns Reviews, 2006 - academic.oup.com
Spindle cell lesions of the thyroid gland (T-SCL) are not encountered routinely in clinical
practice or in the context of thyroid pathology. They commonly are classified as primary or …

Value of routine measurement of serum calcitonin concentrations in patients with nodular thyroid disease: a multicenter study

G Papi, SM Corsello, K Cioni, AM Pizzini… - Journal of …, 2006 - Springer
Background: The routine measurement of serum calcitonin (CT) has been proposed for
patients with nodular thyroid disease (NTD), to detect unsuspected medullary thyroid …

Classical point mutations of RET, BRAF and RAS oncogenes are not shared in papillary and medullary thyroid cancer occurring simultaneously in the same gland

R Ciampi, C Romei, L Pieruzzi, A Tacito… - Journal of …, 2017 - Springer
Background Papillary (PTC) and medullary (MTC) thyroid carcinomas represent two distinct
entities, but quite frequently, they may occur simultaneously. Aim To provide genetic …

Papillary and medullary thyroid carcinomas presenting as collision tumors: a case series of 21 cases at a tertiary care cancer center

A Thomas, N Mittal, SU Rane, M Bal, A Patil… - Head and Neck …, 2021 - Springer
Collision tumor is the occurrence of two histologically and morphologically distinct tumors
within the same organ with no histological admixture. Collision tumors of the thyroid are …

Medullary and papillary carcinoma of the thyroid gland occurring as a collision tumor with lymph node metastasis: A case report

M Sadat Alavi, N Azarpira - Journal of medical case reports, 2011 - Springer
Introduction Papillary thyroid carcinoma and medullary thyroid carcinoma are two different
thyroid neoplasia. The simultaneous occurrence of medullary thyroid carcinoma and …