[HTML][HTML] Animal exercise studies in cardiovascular research: Current knowledge and optimal design—A position paper of the Committee on Cardiac Rehabilitation …
Y Bei, L Wang, R Ding, L Che, Z Fan, W Gao… - Journal of Sport and …, 2021 - Elsevier
Growing evidence has demonstrated exercise as an effective way to promote cardiovascular
health and protect against cardiovascular diseases However, the underlying mechanisms of …
health and protect against cardiovascular diseases However, the underlying mechanisms of …
[HTML][HTML] MiR-223-3p in cardiovascular diseases: a biomarker and potential therapeutic target
MW Zhang, YJ Shen, J Shi, JG Yu - Frontiers in Cardiovascular …, 2021 - frontiersin.org
Cardiovascular diseases, involving vasculopathy, cardiac dysfunction, or circulatory
disturbance, have become the major cause of death globally and brought heavy social …
disturbance, have become the major cause of death globally and brought heavy social …
Role of pregnancy hormones and hormonal interaction on the maternal cardiovascular system: a literature review
Hormones have a vital duty in the conservation of physiological cardiovascular function
during pregnancy. Alterations in oestrogen, progesterone and prolactin levels are …
during pregnancy. Alterations in oestrogen, progesterone and prolactin levels are …
Long-term biased β-arrestin signaling improves cardiac structure and function in dilated cardiomyopathy
Background: Biased agonism of the angiotensin II receptor is known to promote cardiac
contractility. Our laboratory indicated that these effects may be attributable to changes at the …
contractility. Our laboratory indicated that these effects may be attributable to changes at the …
The HVCN1 voltage‐gated proton channel contributes to pH regulation in canine ventricular myocytes
J Ma, X Gao, Y Li, TE DeCoursey… - The Journal of …, 2022 - Wiley Online Library
Regulation of intracellular pH (pHi) in cardiomyocytes is crucial for cardiac function;
however, currently known mechanisms for direct or indirect extrusion of acid from …
however, currently known mechanisms for direct or indirect extrusion of acid from …
PAE ameliorates doxorubicin-induced cardiotoxicity via suppressing NHE1 phosphorylation and stimulating PI3K/AKT phosphorylation
Y Yin, Q Niu, H Hou, H Que, S Mi, J Yang, Z Li… - International …, 2022 - Elsevier
Abstract Doxorubicin (DOX), a broad-spectrum anti-tumor drug, has severe cardiotoxic side
effects that limit its clinical application. Perillaldehyde (PAE) is the main component of …
effects that limit its clinical application. Perillaldehyde (PAE) is the main component of …
[HTML][HTML] Overexpression of miR-223 tips the balance of pro-and anti-hypertrophic signaling cascades toward physiologic cardiac hypertrophy
MicroRNAs (miRNAs) have been extensively examined in pathological cardiac hypertrophy.
However, few studies focused on profiling the miRNA alterations in physiological …
However, few studies focused on profiling the miRNA alterations in physiological …
Cardioprotective role of IGF‐1 in the hypertrophied myocardium of the spontaneously hypertensive rats: a key effect on NHE‐1 activity
Abstract Aim Myocardial Na+/H+ exchanger‐1 (NHE‐1) hyperactivity and oxidative stress
are interrelated phenomena playing pivotal roles in the development of pathological cardiac …
are interrelated phenomena playing pivotal roles in the development of pathological cardiac …
Adding dimension to cellular mechanotransduction: Advances in biomedical engineering of multiaxial cell-stretch systems and their application to cardiovascular …
O Friedrich, D Schneidereit, YA Nikolaev… - Progress in biophysics …, 2017 - Elsevier
Hollow organs (eg heart) experience pressure-induced mechanical wall stress sensed by
molecular mechano-biosensors, including mechanosensitive ion channels, to translate into …
molecular mechano-biosensors, including mechanosensitive ion channels, to translate into …