Imaging advances in chronic obstructive pulmonary disease. Insights from the genetic epidemiology of chronic obstructive pulmonary disease (COPDGene) study

SP Bhatt, GR Washko, EA Hoffman… - American journal of …, 2019 - atsjournals.org
The Genetic Epidemiology of Chronic Obstructive Pulmonary Disease (COPDGene) study,
which began in 2007, is an ongoing multicenter observational cohort study of more than …

[HTML][HTML] Validated imaging biomarkers as decision-making tools in clinical trials and routine practice: current status and recommendations from the EIBALL …

NM deSouza, E Achten, A Alberich-Bayarri… - Insights into …, 2019 - Springer
Observer-driven pattern recognition is the standard for interpretation of medical images. To
achieve global parity in interpretation, semi-quantitative scoring systems have been …

Sex differences in airways at chest CT: results from the COPDGene cohort

SP Bhatt, S Bodduluri, A Nakhmani, Y Kim… - Radiology, 2022 - pubs.rsna.org
Background The prevalence of chronic obstructive pulmonary disease (COPD) in women is
fast approaching that in men, and women experience greater symptom burden. Although …

American Thoracic Society/National Heart, Lung, and Blood Institute asthma–chronic obstructive pulmonary disease overlap workshop report

PG Woodruff, M Van Den Berge… - American journal of …, 2017 - atsjournals.org
Asthma and chronic obstructive pulmonary disease (COPD) are highly prevalent chronic
obstructive lung diseases with an associated high burden of disease. Asthma, which is often …

Comparison of spatially matched airways reveals thinner airway walls in COPD. The Multi-Ethnic Study of Atherosclerosis (MESA) COPD Study and the …

BM Smith, EA Hoffman, D Rabinowitz, E Bleecker… - Thorax, 2014 - thorax.bmj.com
Background COPD is characterised by reduced airway lumen dimensions and fewer
peripheral airways. Most studies of airway properties sample airways based upon lumen …

Analysis of airway pathology in COPD using a combination of computed tomography, micro-computed tomography and histology

N Tanabe, DM Vasilescu, M Kirby… - European …, 2018 - Eur Respiratory Soc
The small conducting airways are the major site of obstruction in chronic obstructive
pulmonary disease (COPD). This study examined small airway pathology using a novel …

[HTML][HTML] Airway wall thickening on CT: relation to smoking status and severity of COPD

JP Charbonnier, E Pompe, C Moore, S Humphries… - Respiratory …, 2019 - Elsevier
Airway wall thickening in cigarette smokers is thought to be a result of inflammatory changes
and airway remodeling. This study investigates if CT-derived airway wall thickening …

Quantitative imaging metrics for the assessment of pulmonary pathophysiology: an official American Thoracic Society and Fleischner Society joint workshop report

CCW Hsia, JHT Bates, B Driehuys, SB Fain… - Annals of the …, 2023 - atsjournals.org
Multiple thoracic imaging modalities have been developed to link structure to function in the
diagnosis and monitoring of lung disease. Volumetric computed tomography (CT) renders …

Recent advances in computed tomography imaging in chronic obstructive pulmonary disease

S Bodduluri, JM Reinhardt, EA Hoffman… - Annals of the …, 2018 - atsjournals.org
Lung imaging is increasingly being used to diagnose, quantify, and phenotype chronic
obstructive pulmonary disease (COPD). Although spirometry is the gold standard for the …

[HTML][HTML] Airway fractal dimension predicts respiratory morbidity and mortality in COPD

S Bodduluri, ASK Puliyakote, SE Gerard… - The Journal of …, 2018 - Am Soc Clin Investig
BACKGROUND. Chronic obstructive pulmonary disease (COPD) is characterized by airway
remodeling. Characterization of airway changes on computed tomography has been …