Camels have an important role in the lives of human beings, especially in arid regions, due
to their multipurpose role and unique ability to adapt to harsh conditions. In spite of its …

This paper is the outcome of the fourth UC Davis Systems Approach to Understanding
Cardiac Excitation–Contraction Coupling and Arrhythmias Symposium, a biannual event …

Background: Small-conductance Ca2+-activated K+ (SK)–channel inhibitors have
antiarrhythmic effects in animal models of atrial fibrillation (AF), presenting a potential novel …

Aims Small-conductance calcium-activated potassium (SK) channels are expressed in the
heart of various species, including humans. The aim of the present study was to address …

The light responses of rod and cone photoreceptors have been studied
electrophysiologically for decades, largely with ex vivo approaches that disrupt the …

The sarcomere is the smallest functional unit of muscle contraction. It is delineated by a
protein-rich structure known as the Z-disk, alternating with M-bands. The Z-disk anchors the …

Cholinergic efferent neurons originating in the brainstem innervate the acoustico-lateralis
organs (inner ear, lateral line) of vertebrates. These release acetylcholine (ACh) to inhibit …

α-Actinins are a major class of actin filament cross-linking proteins expressed in virtually all
cells. In muscle, actinins cross-link thin filaments from adjacent sarcomeres. In non-muscle …

Ca2+-activated K+ channels are critical to cellular Ca2+ homeostasis and excitability; they
couple intracellular Ca2+ and membrane voltage change. Of these, the small, 4–14 pS …

Abstract Small-conductance Ca 2+-activated K+(SK, K Ca 2) channels are encoded by
KCNN genes, including KCNN 1, 2, and 3. The channels play critical roles in the regulation …