Direct cell reprogramming: approaches, mechanisms and progress
The reprogramming of somatic cells with defined factors, which converts cells from one
lineage into cells of another, has greatly reshaped our traditional views on cell identity and …
lineage into cells of another, has greatly reshaped our traditional views on cell identity and …
[HTML][HTML] Biomaterial–related cell microenvironment in tissue engineering and regenerative medicine
J Gao, X Yu, X Wang, Y He, J Ding - Engineering, 2022 - Elsevier
An appropriate cell microenvironment is key to tissue engineering and regenerative
medicine. Revealing the factors that influence the cell microenvironment is a fundamental …
medicine. Revealing the factors that influence the cell microenvironment is a fundamental …
Tissue extracellular matrix hydrogels as alternatives to Matrigel for culturing gastrointestinal organoids
Matrigel, a mouse tumor extracellular matrix protein mixture, is an indispensable component
of most organoid tissue culture. However, it has limited the utility of organoids for drug …
of most organoid tissue culture. However, it has limited the utility of organoids for drug …
Microfluidic device with brain extracellular matrix promotes structural and functional maturation of human brain organoids
Brain organoids derived from human pluripotent stem cells provide a highly valuable in vitro
model to recapitulate human brain development and neurological diseases. However, the …
model to recapitulate human brain development and neurological diseases. However, the …
3D high-density microelectrode array with optical stimulation and drug delivery for investigating neural circuit dynamics
Investigation of neural circuit dynamics is crucial for deciphering the functional connections
among regions of the brain and understanding the mechanism of brain dysfunction. Despite …
among regions of the brain and understanding the mechanism of brain dysfunction. Despite …
Fungal brain infection modelled in a human-neurovascular-unit-on-a-chip with a functional blood–brain barrier
The neurovascular unit, which consists of vascular cells surrounded by astrocytic end-feet
and neurons, controls cerebral blood flow and the permeability of the blood–brain barrier …
and neurons, controls cerebral blood flow and the permeability of the blood–brain barrier …
Gastrointestinal tract modeling using organoids engineered with cellular and microbiota niches
The recent emergence of organoid technology has attracted great attention in
gastroenterology because the gastrointestinal (GI) tract can be recapitulated in vitro using …
gastroenterology because the gastrointestinal (GI) tract can be recapitulated in vitro using …
Concentrically integrative bioassembly of a three-dimensional black phosphorus nanoscaffold for restoring neurogenesis, angiogenesis, and immune homeostasis
Y Qian, WE Yuan, Y Cheng, Y Yang, X Qu, C Fan - Nano Letters, 2019 - ACS Publications
Black phosphorus is well known for its excellent electromechanical properties. Although it
has previously been used for therapeutic drug delivery in cancer, it has never been applied …
has previously been used for therapeutic drug delivery in cancer, it has never been applied …
[HTML][HTML] Brain-on-a-chip: A history of development and future perspective
Since the advent of organ-on-a-chip, many researchers have tried to mimic the physiology of
human tissue on an engineered platform. In the case of brain tissue, structural connections …
human tissue on an engineered platform. In the case of brain tissue, structural connections …
Microfluidics for neuronal cell and circuit engineering
The widespread adoption of microfluidic devices among the neuroscience and neurobiology
communities has enabled addressing a broad range of questions at the molecular, cellular …
communities has enabled addressing a broad range of questions at the molecular, cellular …