Targeting innate immunity-driven inflammation in CKD and cardiovascular disease
T Speer, S Dimmeler, SJ Schunk, D Fliser… - Nature Reviews …, 2022 - nature.com
Mortality among patients with chronic kidney disease (CKD) is largely a consequence of
cardiovascular disease (CVD) and is a particular concern given the increasing prevalence of …
cardiovascular disease (CVD) and is a particular concern given the increasing prevalence of …
Pharmacological therapeutics targeting RNA-dependent RNA polymerase, proteinase and spike protein: from mechanistic studies to clinical trials for COVID-19
An outbreak of novel coronavirus-related pneumonia COVID-19, that was identified in
December 2019, has expanded rapidly, with cases now confirmed in more than 211 …
December 2019, has expanded rapidly, with cases now confirmed in more than 211 …
Review on inflammation markers in chronic kidney disease
Chronic kidney disease (CKD) is one of the major health problems of the modern age. It
represents an important public health challenge with an ever-lasting rising prevalence …
represents an important public health challenge with an ever-lasting rising prevalence …
Lipoproteins in chronic kidney disease: from bench to bedside
T Speer, PM Ridker, A von Eckardstein… - European Heart …, 2021 - academic.oup.com
Chronic kidney disease (CKD) is associated with high cardiovascular risk. CKD patients
exhibit a specific lipoprotein pattern termed 'uraemic dyslipidaemia', which is characterized …
exhibit a specific lipoprotein pattern termed 'uraemic dyslipidaemia', which is characterized …
Tissue sodium accumulation induces organ inflammation and injury in chronic kidney disease
Y Ito, T Sun, H Tanaka, M Yamaguchi… - International Journal of …, 2023 - mdpi.com
High salt intake is a primary cause of over-hydration in chronic kidney disease (CKD)
patients. Inflammatory markers are predictors of CKD mortality; however, the pathogenesis …
patients. Inflammatory markers are predictors of CKD mortality; however, the pathogenesis …
The role of IL-1 in adipose browning and muscle wasting in CKD-associated cachexia
WW Cheung, R Zheng, S Hao, Z Wang, A Gonzalez… - Scientific Reports, 2021 - nature.com
Cytokines such as IL-6, TNF-α and IL-1β trigger inflammatory cascades which may play a
role in the pathogenesis of chronic kidney disease (CKD)-associated cachexia. CKD was …
role in the pathogenesis of chronic kidney disease (CKD)-associated cachexia. CKD was …
Current understanding of the relationship of HDL composition, structure and function to their cardioprotective properties in chronic kidney disease
In the general population, the ability of high-density lipoproteins (HDLs) to promote
cholesterol efflux is a predictor of cardiovascular events, independently of HDL cholesterol …
cholesterol efflux is a predictor of cardiovascular events, independently of HDL cholesterol …
Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: a new paradigm for drug discovery
Epidemiological results revealed that there is an inverse correlation between high-density
lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease …
lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease …
Interleukin-6 blockade reduces salt-induced cardiac inflammation and fibrosis in subtotal nephrectomized mice
H Tanaka, T Sun, H Kinashi, K Kamiya… - American Journal …, 2022 - journals.physiology.org
Cardiovascular disease is the most common comorbidity in patients with chronic kidney
disease (CKD), affecting both their prognosis and quality of life. Cardiac fibrosis is common …
disease (CKD), affecting both their prognosis and quality of life. Cardiac fibrosis is common …
Inflammation, lymphatics, and cardiovascular disease: amplification by chronic kidney disease
Abstract Purpose of Review Kidney disease is a strong modulator of the composition and
metabolism of the intestinal microbiome that produces toxins and inflammatory factors. The …
metabolism of the intestinal microbiome that produces toxins and inflammatory factors. The …