Synaptic reorganization of synchronized neuronal networks with synaptic weight and structural plasticity
Abnormally strong neural synchronization may impair brain function, as observed in several
brain disorders. We computationally study how neuronal dynamics, synaptic weights, and …
brain disorders. We computationally study how neuronal dynamics, synaptic weights, and …
Repetitive transcranial magnetic stimulation (rTMS) triggers dose-dependent homeostatic rewiring in recurrent neuronal networks
Repetitive transcranial magnetic stimulation (rTMS) is a non-invasive brain stimulation
technique used to induce neuronal plasticity in healthy individuals and patients. Designing …
technique used to induce neuronal plasticity in healthy individuals and patients. Designing …
Neurostimulation targeting the epileptic focus: Current understanding and perspectives for treatment
For the one third of people with epilepsy whose seizures are not controlled with medications,
targeting the seizure focus with neurostimulation can be an effective therapeutic strategy. In …
targeting the seizure focus with neurostimulation can be an effective therapeutic strategy. In …
Altered pain sensitivity in 5× familial Alzheimer disease mice is associated with dendritic spine loss in anterior cingulate cortex pyramidal neurons
Z Cui, Z Guo, L Wei, X Zou, Z Zhu, Y Liu, J Wang… - Pain, 2022 - journals.lww.com
Chronic pain is highly prevalent. Individuals with cognitive disorders such as Alzheimer
disease are a susceptible population in which pain is frequently difficult to diagnosis. It is still …
disease are a susceptible population in which pain is frequently difficult to diagnosis. It is still …
Interplay between homeostatic synaptic scaling and homeostatic structural plasticity maintains the robust firing rate of neural networks
Critical network states and neural plasticity are essential for flexible behavior in an ever-
changing environment, which allows for efficient information processing and experience …
changing environment, which allows for efficient information processing and experience …
Calcium imaging reveals depressive-and manic-phase-specific brain neural activity patterns in a murine model of bipolar disorder: a pilot study
M Chen, H Tian, G Huang, T Fang, X Lin, J Shan… - Translational …, 2021 - nature.com
Brain pathological features during manic/hypomanic and depressive episodes in the same
patients with bipolar disorder (BPD) have not been described precisely. The study aimed to …
patients with bipolar disorder (BPD) have not been described precisely. The study aimed to …
Clozapine-Induced Chemogenetic Neuromodulation Rescues Post-Stroke Deficits After Chronic Capsular Infarct
J Cho, S Ryu, S Lee, J Kim, JY Park, HS Kwon… - Translational Stroke …, 2023 - Springer
Long-term disabilities induced by stroke impose a heavy burden on patients, families,
caregivers, and public health systems. Extensive studies have demonstrated the therapeutic …
caregivers, and public health systems. Extensive studies have demonstrated the therapeutic …
Antiepileptic medication strengthens excitatory neurotransmission in pyramidal neurons of the adult human neocortex
M Lenz, P Kruse, A Eichler, J Straehle, H Hemeling… - bioRxiv, 2023 - biorxiv.org
Homeostatic synaptic plasticity serves to maintain neuronal function within a dynamic range
upon perturbations in network activity. While coordinated structural and functional changes …
upon perturbations in network activity. While coordinated structural and functional changes …