Autoimmune diseases (AID) are a collection of many complex disorders of unknown etiology
resulting in immune responses to self-antigens and are thought to result from interactions …

Background: In support of the Integrated Risk Information System (IRIS), the US
Environmental Protection Agency (EPA) completed a toxicological review of …

Scleroderma [also known as systemic sclerosis (SSc)] is a complex autoimmune disease
characterised by pathological remodelling of connective tissues. Although the earliest and …

Organic solvents are widely employed in industry and are used in large quantities across the
world. A solvent can be defined as ''a liquid that has the ability to dissolve, suspend or …

The etiology of systemic sclerosis (SSc) remains unknown; however, several occupational
and environmental factors have been implicated. Our objective was to perform a meta …

Background Genetic and epigenetic factors interacting with the environment over time are
the main causes of complex diseases such as autoimmune diseases (ADs). Among the …

Abstract Introduction Systemic sclerosis (SSc) has complex pathogenesis and likely
multifactorial causes. Environmental exposures have been suggested to play a role in SSc …

In recent years, considerable interest has been focused on curcumin a compound, isolated
from turmeric. Curcumin is used as a coloring, flavoring agent and has been traditionally …

Objectives Among potential environmental risk factors for systemic sclerosis (SSc),
occupational exposures have received some attention. In this meta-analysis, we examined …

Objective Our objective was to examine experimental and epidemiologic studies pertaining
to immune-related, and specifically autoimmune-related, effects of trichloroethylene (TCE) …