A Review of Probabilistic Genotyping Systems: EuroForMix, DNAStatistX and STRmix™
Probabilistic genotyping has become widespread. EuroForMix and DNAStatistX are both
based upon maximum likelihood estimation using a γ model, whereas STRmix™ is a …
based upon maximum likelihood estimation using a γ model, whereas STRmix™ is a …
A large-scale dataset of single and mixed-source short tandem repeat profiles to inform human identification strategies: PROVEDIt
DNA-based human identity testing is conducted by comparison of PCR-amplified
polymorphic Short Tandem Repeat (STR) motifs from a known source with the STR profiles …
polymorphic Short Tandem Repeat (STR) motifs from a known source with the STR profiles …
Estimating the number of contributors to a DNA profile using decision trees
The interpretation of DNA profiles typically starts with an assessment of the number of
contributors. In the last two decades, several methods have been proposed to assist with this …
contributors. In the last two decades, several methods have been proposed to assist with this …
Automated estimation of the number of contributors in autosomal short tandem repeat profiles using a machine learning approach
CCG Benschop, J van der Linden… - Forensic science …, 2019 - Elsevier
The number of contributors (NOC) to (complex) autosomal STR profiles cannot be
determined with absolute certainty due to complicating factors such as allele sharing and …
determined with absolute certainty due to complicating factors such as allele sharing and …
Complex DNA mixture analysis in a forensic context: evaluating the probative value using a likelihood ratio model
The interpretation of mixed DNA profiles obtained from low template DNA samples has
proven to be a particularly difficult task in forensic casework. Newly developed likelihood …
proven to be a particularly difficult task in forensic casework. Newly developed likelihood …
[HTML][HTML] Machine learning applications in forensic DNA profiling: A critical review
Abstract Machine learning (ML) is a range of powerful computational algorithms capable of
generating predictive models via intelligent autonomous analysis of relatively large and …
generating predictive models via intelligent autonomous analysis of relatively large and …
Estimating number of contributors in massively parallel sequencing data of STR loci
In recent years a number of computer-based algorithms have been developed for the
deconvolution of complex DNA mixtures in forensic science. These procedures utilize …
deconvolution of complex DNA mixtures in forensic science. These procedures utilize …
The effect of varying the number of contributors on likelihood ratios for complex DNA mixtures
Abstract Interpretation of DNA mixtures with three or more contributors, defined here as high
order mixtures, is difficult because of the inevitability of allele sharing. Allele sharing …
order mixtures, is difficult because of the inevitability of allele sharing. Allele sharing …
MaSTR™: an effective probabilistic genotyping tool for interpretation of STR mixtures associated with differentially degraded DNA
MM Holland, TM Tiedge, AJ Bender… - International Journal of …, 2022 - Springer
The recently developed probabilistic genotyping software package MaSTR™(SoftGenetics
LLC) was used to develop statistical weight estimates for a variety of two-person STR …
LLC) was used to develop statistical weight estimates for a variety of two-person STR …
Inferring the number of contributors to complex DNA mixtures using three methods: exploring the limits of low‐template DNA interpretation
LE Alfonse, G Tejada, H Swaminathan… - Journal of forensic …, 2017 - Wiley Online Library
In forensic DNA casework, the interpretation of an evidentiary profile may be dependent
upon the assumption on the number of individuals from whom the evidence arose. Three …
upon the assumption on the number of individuals from whom the evidence arose. Three …