Over the past decade, RNA sequencing (RNA-seq) has become an indispensable tool for
transcriptome-wide analysis of differential gene expression and differential splicing of …

The application of sequencing technology is shifting from research to clinical laboratories
owing to rapid technological developments and substantially reduced costs. However …

Assessment of bacterial diversity through sequencing of 16S ribosomal RNA (16S rRNA)
genes has been an approach widely used in environmental microbiology, particularly since …

Dormant prophages protect lysogenic cells by expressing diverse immune systems, which
must avoid targeting their cognate prophages upon activation. Here we report that multiple …

With the invention of RNA sequencing over a decade ago, diagnosis and identification of the
gene-related diseases entered a new phase that enabled more accurate analysis of the …

Abstract Adenosine Deaminases that Act on RNA (ADARs) are RNA editing enzymes that
play a dynamic and nuanced role in regulating transcriptome and proteome diversity. This …

Long-read sequencing (LRS) has become increasingly popular due to its strengths in de
novo assembly and in resolving complex DNA regions as well as in determining full-length …

Infectious disease is still a major threat in the world today. Five decades ago, it was
considered soon to be eradicated, but the adaptation of pathogens to environmental …

Background Alternative splicing is a key step in Human Immunodeficiency Virus type 1 (HIV-
1) replication that is tightly regulated both temporally and spatially. More than 50 different …

Long-read sequencing (LRS) techniques enable the identification of full-length RNA
molecules in a single run eliminating the need for additional assembly steps. LRS research …