Progesterone actions and resistance in gynecological disorders

JA MacLean, K Hayashi - Cells, 2022 - mdpi.com
Estrogen and progesterone and their signaling mechanisms are tightly regulated to maintain
a normal menstrual cycle and to support a successful pregnancy. The imbalance of estrogen …

Assessing research gaps and unmet needs in endometriosis

S As-Sanie, R Black, LC Giudice, TG Valbrun… - American journal of …, 2019 - Elsevier
Endometriosis, a systemic disease that is often painful and chronic, affects∼ 10% of
reproductive-age women. The disease can have a negative impact on a patient's physical …

Clinical practice guidelines for antimicrobial prophylaxis in surgery

DW Bratzler, EP Dellinger, KM Olsen, TM Perl… - Surgical …, 2013 - liebertpub.com
Infectious Diseases Society of America (IDSA), the Surgical Infection Society (SIS), and the
Society for Healthcare Epidemiology of America (SHEA). This work represents an update to …

Uterine fibroids: diagnosis and treatment

MSD De La Cruz, EM Buchanan - American family physician, 2017 - aafp.org
Uterine fibroids are common benign neoplasms, with a higher prevalence in older women
and in those of African descent. Many are discovered incidentally on clinical examination or …

Cell origins of high-grade serous ovarian cancer

J Kim, EY Park, O Kim, JM Schilder, DM Coffey… - Cancers, 2018 - mdpi.com
High-grade serous ovarian cancer, also known as high-grade serous carcinoma (HGSC), is
the most common and deadliest type of ovarian cancer. HGSC appears to arise from the …

Epidemiology of adenomyosis

K Upson, SA Missmer - Seminars in reproductive medicine, 2020 - thieme-connect.com
Adenomyosis, characterized by the presence of endometrial glands and stroma within the
myometrium, can have a substantial impact on the quality of women's lives. Despite this, the …

Environmental impacts of surgical procedures: life cycle assessment of hysterectomy in the United States

CL Thiel, M Eckelman, R Guido… - … science & technology, 2015 - ACS Publications
The healthcare sector is a driver of economic growth in the US, with spending on healthcare
in 2012 reaching $2.8 trillion, or 17% of the US gross domestic product, but it is also a …

Long-term mortality associated with oophorectomy compared with ovarian conservation in the nurses' health study

WH Parker, D Feskanich, MS Broder… - Obstetrics & …, 2013 - journals.lww.com
OBJECTIVE: To report long-term mortality after oophorectomy or ovarian conservation at the
time of hysterectomy in subgroups of women based on age at the time of surgery, use of …

Age of menopause and impact of climacteric symptoms by geographical region

S Palacios, VW Henderson, N Siseles, D Tan… - …, 2010 - Taylor & Francis
Objective To describe differences in the age of onset of menopause and in the prevalence of
climacteric symptoms in different geographical areas. Design Systematic review of …

Pelvic organ prolapse

MD Barber - Bmj, 2016 - bmj.com
A woman's lifetime risk of surgery for pelvic organ prolapse (POP) is 12-19% with over 300
000 prolapse surgeries performed annually in the US alone. 1-3 POP accounts for about 15 …