Role of Na+/K+-ATPase in ischemic stroke: in-depth perspectives from physiology to pharmacology
Abstract Na+/K+-ATPase (NKA) is a large transmembrane protein expressed in all cells. It is
well studied for its ion exchanging function, which is indispensable for the maintenance of …
well studied for its ion exchanging function, which is indispensable for the maintenance of …
Hypoxic stress-dependent regulation of Na, K-ATPase in ischemic heart disease
E Baloglu - International Journal of Molecular Sciences, 2023 - mdpi.com
In cardiomyocytes, regular activity of the Na, K-ATPase (NKA) and its Na/K pump activity is
essential for maintaining ion gradients, excitability, propagation of action potentials, electro …
essential for maintaining ion gradients, excitability, propagation of action potentials, electro …
Na, K-ATPase acts as a beta-amyloid receptor triggering src kinase activation
IY Petrushanko, AM Tverskoi, EP Barykin… - Cells, 2022 - mdpi.com
Beta-amyloid (Aβ) has a dual role, both as an important factor in the pathology of
Alzheimer's disease and as a regulator in brain physiology. The inhibitory effect of Aβ42 …
Alzheimer's disease and as a regulator in brain physiology. The inhibitory effect of Aβ42 …
The Na/K-ATPase α1 and c-Src form signaling complex under native condition: A crosslinking approach
The protein-protein interactions amongst the Na/K-ATPase α1 subunit, c-Src, and caveolin-1
(cav-1) are essential for the Na/K-ATPase signaling functions. However, there are …
(cav-1) are essential for the Na/K-ATPase signaling functions. However, there are …
Oral digoxin effects on exercise performance, K+ regulation and skeletal muscle Na+,K+‐ATPase in healthy humans
S Sostaric, AC Petersen, CA Goodman… - The Journal of …, 2022 - Wiley Online Library
We investigated whether digoxin lowered muscle Na+, K+‐ATPase (NKA), impaired muscle
performance and exacerbated exercise K+ disturbances. Ten healthy adults ingested …
performance and exacerbated exercise K+ disturbances. Ten healthy adults ingested …
Glutathione-related substances maintain cardiomyocyte contractile function in hypoxic conditions
YM Poluektov, IY Petrushanko, NA Undrovinas… - Scientific Reports, 2019 - nature.com
Severe hypoxia leads to decline in cardiac contractility and induces arrhythmic events in part
due to oxidative damage to cardiomyocyte proteins including ion transporters. This results in …
due to oxidative damage to cardiomyocyte proteins including ion transporters. This results in …
[HTML][HTML] Fermencin B2: A promising heat-stable cationic peptide for targeted inhibition of Staphylococcus aureus
J Xu, X Fan, Y Hu, M Liu, L Du, Z Wu, M Tu, N Ling… - LWT, 2024 - Elsevier
In this study, a novel strain of L. fermentum JF9 with bacteriocin production capacity was
firstly isolated from Chinese fermented vinegar Pei, and the significant antibacterial potential …
firstly isolated from Chinese fermented vinegar Pei, and the significant antibacterial potential …
[HTML][HTML] Redox regulation of glutathione peroxidase by thioredoxin in longan fruit in relation to senescence and quality deterioration
F Wu, G Jiang, H Yan, L Xiao, H Liang, D Zhang… - Food Chemistry, 2021 - Elsevier
Thioredoxins (Trxs) are important redox regulators in organisms. However, their involvement
in fruit senescence and quality deterioration remains unclear. In this study, one Trx (DlTrx1) …
in fruit senescence and quality deterioration remains unclear. In this study, one Trx (DlTrx1) …
The redox-sensitive Na/K-ATPase signaling in uremic cardiomyopathy
In recent years, Na/K-ATPase signaling has been implicated in different physiological and
pathophysiological conditions, including cardiac hypertrophy and uremic cardiomyopathy …
pathophysiological conditions, including cardiac hypertrophy and uremic cardiomyopathy …
Metabolic syndrome and salt-sensitive hypertension in polygenic obese TALLYHO/JngJ mice: role of Na/K-ATPase signaling
We have demonstrated that Na/K-ATPase acts as a receptor for reactive oxygen species
(ROS), regulating renal Na+ handling and blood pressure. TALLYHO/JngJ (TH) mice are …
(ROS), regulating renal Na+ handling and blood pressure. TALLYHO/JngJ (TH) mice are …