The vascular endothelial glycocalyx is a dense, bush-like structure that is synthesized and
secreted by endothelial cells and evenly distributed on the surface of vascular endothelial …

Abstracts Background The number of studies measuring breakdown products of the
glycocalyx in plasma has increased rapidly during the past decade. The purpose of the …

Delayed cerebral ischemia (DCI) is the most feared complication of aneurysmal
subarachnoid hemorrhage (aSAH). It increases the mortality and morbidity associated with …

Aneurysmal subarachnoid hemorrhage (aSAH) represents only a small portion of all strokes,
but accounts for almost half of the deaths caused by stroke worldwide. Neurosurgical …

Background No new therapies for traumatic brain injury (TBI) have been officially translated
into current practice. At the tissue and cellular level, both inflammatory and oxidative …

Aneurysms are malformations within the arterial vasculature brought on by the structural
breakdown of the microarchitecture of the vessel wall, with aneurysms posing serious health …

The socio-economic impact of diseases associated with cognitive impairment is increasing.
According to the Alzheimer's Society there are over 850,000 people with dementia in the UK …

Poor outcomes of aneurysmal subarachnoid hemorrhage (aSAH) can be the result of the
initial catastrophic event or the many acute or delayed neurological complications. Recent …

OBJECTIVE Delayed cerebral ischemia (DCI) and aneurysm rebleeding contribute to
morbidity and mortality in aneurysmal subarachnoid hemorrhage (aSAH); however, the …

Background The high mortality and morbidity after SAH is partly due to DCI, which is
traditionally ascribed to development of angiographic vasospasms. This relation has been …