[HTML][HTML] Is melatonin the cornucopia of the 21st century?

N Ferlazzo, G Andolina, A Cannata, MG Costanzo… - Antioxidants, 2020 - mdpi.com
Melatonin, an indoleamine hormone produced and secreted at night by pinealocytes and
extra-pineal cells, plays an important role in timing circadian rhythms (24-h internal clock) …

Melatonin and cancer hallmarks

WH Talib - Molecules, 2018 - mdpi.com
Melatonin is a natural indoleamine produced by the pineal gland that has many functions,
including regulation of the circadian rhythm. Many studies have reported the anticancer …

Dietary phytochemicals in breast cancer research: anticancer effects and potential utility for effective chemoprevention

A Kapinova, P Kubatka, O Golubnitschaja… - … health and preventive …, 2018 - Springer
Cancerous tissue transformation developing usually over years or even decades of life is a
highly complex process involving strong stressors damaging DNA, chronic inflammation …

Exploring the mechanical perspective of a new anti-tumor agent: melatonin

S Rohilla, M Singh, S Priya, WH Almalki… - Journal of …, 2023 - dl.begellhouse.com
Melatonin is a serotonin-derived pineal gland hormone with many biological functions like
regulating the sleep-wake cycle, circadian rhythm, menstrual cycle, aging, immunity, and …

An overview of melatonin as an antioxidant molecule: a biochemical approach

A Hacışevki, B Baba - Melatonin molecular biology, clinical and …, 2018 - books.google.com
Melatonin is an endogenous hormone derived from tryptophan that is mainly released from
the pineal gland in the dark. Melatonin regulates many biological functions such as sleep …

Melatonin as a regulator of apoptosis in leukaemia: molecular mechanism and therapeutic perspectives

A Mafi, H Rismanchi, Y Gholinezhad… - Frontiers in …, 2023 - frontiersin.org
Leukaemia is a dangerous malignancy that causes thousands of deaths every year
throughout the world. The rate of morbidity and mortality is significant despite many …

Antioxidants for the treatment of breast cancer: Are we there yet?

C Griñan-Lison, JL Blaya-Cánovas, A López-Tejada… - Antioxidants, 2021 - mdpi.com
Breast cancer is the most frequent cancer and the leading cause of cancer death in women.
Oxidative stress and the generation of reactive oxygen species (ROS) have been related to …

Melatonin, an ubiquitous metabolic regulator: functions, mechanisms and effects on circadian disruption and degenerative diseases

AI Socaciu, R Ionuţ, MA Socaciu, AP Ungur… - Reviews in Endocrine …, 2020 - Springer
The last four decades, we assist to an increasing scientific interest on melatonin, a circadian
hormone, a metabolic regulator which influences not only plants' metabolism and their …

Melatonin reduces proliferation and promotes apoptosis of bladder cancer cells by suppressing O‐GlcNAcylation of cyclin‐dependent‐like kinase 5

J Wu, Z Tan, H Li, M Lin, Y Jiang, L Liang… - Journal of Pineal …, 2021 - Wiley Online Library
Melatonin helps to maintain circadian rhythm, exerts anticancer activity, and plays key roles
in regulation of glucose homeostasis and energy metabolism. Glycosylation, a form of …

Beneficial Effects of Exogenous Melatonin on Overcoming Salt Stress in Sugar Beets (Beta vulgaris L.)

P Zhang, L Liu, X Wang, Z Wang, H Zhang, J Chen… - Plants, 2021 - mdpi.com
Melatonin has been regarded as a promising substance that enhances the abiotic stress
tolerance of plants. However, few studies have devoted attention to the role of melatonin in …