[HTML][HTML] Chitosan oligosaccharides inhibit the fibrillation of insulin and disassemble its preformed fibrils
A Kalitnik, M Grelich-Mucha… - International Journal of …, 2024 - Elsevier
In the current study, we first established that chitosan oligosaccharides (COS) have
significant anti-fibrillogenic and fibril-destabilising effects on bovine insulin in vitro that …
significant anti-fibrillogenic and fibril-destabilising effects on bovine insulin in vitro that …
Unravelling heparin's enhancement of amyloid aggregation in a model peptide system
A coarse-grained (CG) model for heparin, an anionic polysaccharide, was developed to
investigate the mechanisms of heparin's enhancement of fibrillation in many amyloidogenic …
investigate the mechanisms of heparin's enhancement of fibrillation in many amyloidogenic …
Mechanistic insights into the inhibition of amyloid-β aggregation by chitosan
S Gotla, S Matysiak - Physical Chemistry Chemical Physics, 2023 - pubs.rsc.org
Neurodegeneration related to Alzheimer's disease has long been linked to the accumulation
of abnormal aggregates of amyloid-β (Aβ) peptides. Pre-fibrillar oligomeric intermediates of …
of abnormal aggregates of amyloid-β (Aβ) peptides. Pre-fibrillar oligomeric intermediates of …
Amyloidogenicity of the Peptide Fragment in Microtubule Binding Repeat Domain of Tau
M Islam - 2023 - search.proquest.com
Tau, a microtubule-associated protein, is involved in more than 20 different tauopathic
disorders characterized by aberrant intracellular aggregation of tau in the brain. However, it …
disorders characterized by aberrant intracellular aggregation of tau in the brain. However, it …