Postoperative adhesion (POA) widely occurs in soft tissues and usually leads to chronic
pain, dysfunction of adjacent organs and some acute complications, seriously reducing …

Pirfenidone (PFD) is a non-peptide synthetic chemical that inhibits the production of
transforming growth factor-beta 1 (TGF-β1), tumor necrosis factor-alpha (TNF-α), platelet …

Postoperative peritoneal adhesion (PPA) is a serious clinical condition that affects the high
percentage of patients after abdominal surgery. In this review, we have tried to focus on …

Postoperative peritoneal adhesions are considered the major complication following
abdominal surgeries. The primary clinical complications of peritoneal adhesion are intestinal …

Treatment of breast cancer with doxorubicin causes numerous side effects, of which cardiac
fibrosis is considered the main one. This study was designed to investigate the underlying …

Gynaecological health is a neglected field of research that includes conditions such as
endometriosis, uterine fibroids, infertility, viral and bacterial infections, and cancers. There is …

Epidural fibrosis causes serious complications in patients who have undergone
laminectomy. Pirfenidone is an effective antifibrotic agent but its effect on epidural fibrosis …

抄録 Pirfenidone is a representative medication to treat interstitial pulmonary fibrosis.
Researchers reported pirfenidone (> 100 µg/ml) significantly suppressed fibroblast growth in …

Background Intra-abdominal adhesion is one of the most common complications after
abdominal surgery. The efficacy of current treatments for intra-abdominal adhesion is …

Postoperative adhesions are a frequent complication encountered after surgical procedures,
mainly after intraperitoneal interventions. To this day, the pathophysiological mechanism …