The management of bacterial infections is becoming a major clinical challenge due to the
rapid evolution of antibiotic resistant bacteria. As an excellent candidate to overcome …

Antimicrobial peptides are a type of small-molecule peptide that widely exist in nature and
are components of the innate immunity of almost all living things. They play an important role …

Antimicrobial peptides (AMPs) take part in the immune system by mounting a first line of
defense against pathogens. Recurrent structural and functional aspects are observed …

The increase in antibiotic drug resistance and the low number of new antibacterial drugs
approved in the last few decades requires the development of new antimicrobial strategies …

The mode of action of antimicrobial peptides (AMPs) in disrupting cell membrane bilayers is
of fundamental importance in understanding the efficiency of different AMPs, which is crucial …

The innate immunity factor lactoferrin harbours two antimicrobial moieties, lactoferricin and
lactoferrampin, situated in close proximity in the N1 domain of the molecule. Most likely they …

Abstract BP100 (KKLFKKILKYL-NH 2) is a short cecropin A-melittin hybrid peptide, obtained
through a combinatorial chemistry approach, which is highly effective in inhibiting both the in …

Despite recent medical research and clinical practice developments, the development of
antimicrobial resistance (AMR) significantly limits therapeutics for infectious diseases. Thus …

Highly charged peptides are important components of the immune system and belong to an
important family of antibiotics. Although their therapeutic activity is known, most of the …

Melimine is a novel cationic peptide possessing broad-spectrum antimicrobial activity that is
retained when attached to a surface, suggesting that interactions with bacterial membranes …