The application of single-cell RNA sequencing (scRNA-seq) in biomedical research has
advanced our understanding of the pathogenesis of disease and provided valuable insights …

Single-cell technologies have transformed our understanding of human tissues. Yet, studies
typically capture only a limited number of donors and disagree on cell type definitions …

The thalamus plays a central coordinating role in the brain. Thalamic neurons are organized
into spatially distinct nuclei, but the molecular architecture of thalamic development is poorly …

Human-specific genomic changes contribute to the unique functionalities of the human
brain,,,–. The cellular heterogeneity of the human brain, and the complex regulation of gene …

Regenerative medicine and tissue engineering aim to promote functional rebuilding of
damaged tissue. Comprehensively profiling cell identity, function and interaction in healthy …

Neuroblastoma, a rare embryonic tumor arising from neural crest development, is
responsible for 15% of pediatric cancer-related deaths. Recently, several single-cell …

Our ability to understand the cellular complexity of tissues has been revolutionised in recent
years with significant advances in proteogenomic technologies including those enabling …

Sleep deprivation (SD) has negative effects on brain and body function. Sleep problems are
prevalent in a variety of disorders, including neurodevelopmental and psychiatric conditions …

Background In patients with asthma, respiratory syncytial virus (RSV) infections can cause
disease exacerbation by infecting the epithelial layer of the airways, inducing subsequent …

Human Leukocyte Antigen (HLA) is like a device that monitors the internal environment of
the body. T lymphocytes immediately recognize the HLA molecules that are expressed on …