PRIMUS: rapid reconstruction of pedigrees from genome-wide estimates of identity by descent
Understanding and correctly utilizing relatedness among samples is essential for genetic
analysis; however, managing sample records and pedigrees can often be error prone and …
analysis; however, managing sample records and pedigrees can often be error prone and …
Discovering genes involved in disease and the mystery of missing heritability
E Eskin - Communications of the ACM, 2015 - dl.acm.org
Discovering genes involved in disease and the mystery of missing heritability Page 1 80
COMMUNICATIONS OF THE ACM | OCTOBER 2015 | VOL. 58 | NO. 10 review articles DOI:10.1145/2817827 …
COMMUNICATIONS OF THE ACM | OCTOBER 2015 | VOL. 58 | NO. 10 review articles DOI:10.1145/2817827 …
A 472-SNP panel for pairwise kinship testing of second-degree relatives
SK Mo, ZL Ren, YR Yang, YC Liu, JJ Zhang… - Forensic Science …, 2018 - Elsevier
Kinship testing based on genetic markers, as forensic short tandem repeats (STRs) and
single nucleotide polymorphisms (SNPs), has valuable practical applications. Paternity and …
single nucleotide polymorphisms (SNPs), has valuable practical applications. Paternity and …
Composite likelihood method for inferring local pedigrees
Pedigrees contain information about the genealogical relationships among individuals and
are of fundamental importance in many areas of genetic studies. However, pedigrees are …
are of fundamental importance in many areas of genetic studies. However, pedigrees are …
Ancestral haplotype reconstruction in endogamous populations using identity-by-descent
K Finke, M Kourakos, G Brown, HT Dang… - PLoS computational …, 2021 - journals.plos.org
In this work we develop a novel algorithm for reconstructing the genomes of ancestral
individuals, given genotype or sequence data from contemporary individuals and an …
individuals, given genotype or sequence data from contemporary individuals and an …
Iped2: Inheritance path based pedigree reconstruction algorithm for complicated pedigrees
Reconstruction of family trees, or pedigree reconstruction, for a group of individuals is a
fundamental problem in genetics. The problem is known to be NP-hard even for datasets …
fundamental problem in genetics. The problem is known to be NP-hard even for datasets …
Kinlinks: Software toolkit for kinship analysis and pedigree generation from hts datasets
A Shcherbina, DO Ricke, E Schwoebel… - … IEEE Symposium on …, 2016 - ieeexplore.ieee.org
The ability to predict familial relationships from source DNA in multiple samples has a
number of forensic and medical applications. Kinship testing of suspect DNA profiles against …
number of forensic and medical applications. Kinship testing of suspect DNA profiles against …
IBD-Groupon: an efficient method for detecting group-wise identity-by-descent regions simultaneously in multiple individuals based on pairwise IBD relationships
D He - Bioinformatics, 2013 - academic.oup.com
Motivation: Detecting IBD tracts is an important problem in genetics. Most of the existing
methods focus on detecting pairwise IBD tracts, which have relatively low power to detect …
methods focus on detecting pairwise IBD tracts, which have relatively low power to detect …
A likelihood ratio-based method to predict exact pedigrees for complex families from next-generation sequencing data
Motivation Next generation sequencing technology considerably changed the way we
screen for pathogenic mutations in rare Mendelian disorders. However, the identification of …
screen for pathogenic mutations in rare Mendelian disorders. However, the identification of …
Historical pedigree reconstruction from extant populations using PArtitioning of RElatives (PREPARE)
D Shem-Tov, E Halperin - PLoS computational biology, 2014 - journals.plos.org
Recent technological improvements in the field of genetic data extraction give rise to the
possibility of reconstructing the historical pedigrees of entire populations from the genotypes …
possibility of reconstructing the historical pedigrees of entire populations from the genotypes …