A diverse array of sex determination (SD) mechanisms, encompassing environmental to
genetic, have been found to exist among vertebrates, covering a spectrum from fixed SD …

Premature ovarian insufficiency (POI) occurs in at least 1% of all women and causes life-
long health problems and psychological stress. Infertility caused by POI used to be …

The term differences of sex development (DSDs; also known as disorders of sex
development) refers to a heterogeneous group of congenital conditions affecting human sex …

BACKGROUND Primary ovarian insufficiency (POI) is characterized by marked
heterogeneity, but with a significant genetic contribution. Identifying exact causative genes …

Anti-Müllerian hormone (AMH), also called Müllerian inhibiting substance, was shown to be
synthesized by the ovary in the 1980s. This article reviews the main findings of the past 20 …

Ovarian cancer is the fifth cause of cancer-related death in women and comprises a
histologically and genetically broad range of tumours, including those of epithelial, sex cord …

Primary ovarian insufficiency is a subclass of ovarian dysfunction in which the cause is
within the ovary. In most cases, an unknown mechanism leads to premature exhaustion of …

Individuals affected with developmental disorders of speech and language have substantial
difficulty acquiring expressive and/or receptive language in the absence of any profound …

Two major functions of the mammalian ovary are the production of germ cells (oocytes),
which allow continuation of the species, and the generation of bioactive molecules, primarily …

The delay in childbearing is an important societal change contributing to an increasing
incidence of subfertility. The prevailing concept of female reproductive ageing assumes that …