[HTML][HTML] Dengue virus infection–a review of pathogenesis, vaccines, diagnosis and therapy
The transmission of dengue virus (DENV) from an infected Aedes mosquito to a human,
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …
causes illness ranging from mild dengue fever to fatal dengue shock syndrome. The similar …
Antiviral neutralizing antibodies: from in vitro to in vivo activity
DR Burton - Nature Reviews Immunology, 2023 - nature.com
Neutralizing antibodies (nAbs) are being increasingly used as passive antiviral reagents in
prophylactic and therapeutic modalities and to guide viral vaccine design. In vivo, nAbs can …
prophylactic and therapeutic modalities and to guide viral vaccine design. In vivo, nAbs can …
Zika virus structure, maturation, and receptors
The emergence of Zika virus (ZIKV) as a major public health threat has focused research on
understanding virus biology and developing a suite of strategies for disease intervention …
understanding virus biology and developing a suite of strategies for disease intervention …
Structural basis of Zika virus-specific antibody protection
Zika virus (ZIKV) infection during pregnancy has emerged as a global public health problem
because of its ability to cause severe congenital disease. Here, we developed six mouse …
because of its ability to cause severe congenital disease. Here, we developed six mouse …
New insights into the immunopathology and control of dengue virus infection
G Screaton, J Mongkolsapaya, S Yacoub… - Nature Reviews …, 2015 - nature.com
Dengue virus poses a major threat to global public health: two-thirds of the world's
population is now at risk from infection by this mosquito-borne virus. Dengue virus causes a …
population is now at risk from infection by this mosquito-borne virus. Dengue virus causes a …
Secondary infection as a risk factor for dengue hemorrhagic fever/dengue shock syndrome: an historical perspective and role of antibody-dependent enhancement of …
MG Guzman, M Alvarez, SB Halstead - Archives of virology, 2013 - Springer
Today, dengue viruses are the most prevalent arthropod-borne viruses in the world. Since
the 1960s, numerous reports have identified a second heterologous dengue virus (DENV) …
the 1960s, numerous reports have identified a second heterologous dengue virus (DENV) …
The bright and the dark side of human antibody responses to flaviviruses: lessons for vaccine design
FA Rey, K Stiasny, MC Vaney, M Dellarole… - EMBO reports, 2018 - embopress.org
Zika and dengue viruses belong to the Flavivirus genus, a close group of antigenically
related viruses that cause significant arthropod‐transmitted diseases throughout the globe …
related viruses that cause significant arthropod‐transmitted diseases throughout the globe …
Immunity to dengue virus: a tale of original antigenic sin and tropical cytokine storms
AL Rothman - Nature Reviews Immunology, 2011 - nature.com
Dengue is a mosquito-borne viral disease of expanding geographical range and incidence.
The existence of four viral serotypes and the association of prior dengue virus infection with …
The existence of four viral serotypes and the association of prior dengue virus infection with …
Dengue viruses–an overview
A Tuiskunen Bäck, Å Lundkvist - Infection ecology & epidemiology, 2013 - Taylor & Francis
Dengue viruses (DENVs) cause the most common arthropod-borne viral disease in man
with 50–100 million infections per year. Because of the lack of a vaccine and antiviral drugs …
with 50–100 million infections per year. Because of the lack of a vaccine and antiviral drugs …
Structural biology of Zika virus and other flaviviruses
Zika virus (ZIKV) is an enveloped, icosahedral flavivirus that has structural and functional
similarities to other human flavivirus pathogens such as dengue (DENV), West Nile (WNV) …
similarities to other human flavivirus pathogens such as dengue (DENV), West Nile (WNV) …