Animal cell culture technology has advanced significantly over the last few decades and is
now generally considered a reliable, robust and relatively mature technology. A range of …

Mammalian cell culture metabolism is characterized by glucoglutaminolysis, that is, high
glucose and glutamine uptake combined with a high rate of lactate and non-essential amino …

Fed‐batch Chinese hamster ovary (CHO) cell culture is the most commonly used process for
IgG production in the biopharmaceutical industry. Amino acid and glucose consumption, cell …

In this study, eight commercially available, chemically defined Chinese hamster ovary (CHO)
cell culture media from different vendors were evaluated in batch culture using an IgG …

In this study a prominent technique namely grafting of 2‑hydroxy ethyl methacrylate (known
as HEMA) monomer onto modified bleached Agave cantala leaf fibers (ACLF) to fabricate …

Multivariate analysis of cell culture bioprocess data has the potential of unveiling hidden
process characteristics and providing new insights into factors affecting process …

In recent years, metabolomics developed to an accepted and valuable tool in life sciences.
Substantial improvements of analytical hardware allow metabolomics to run routinely now …

Bioreactor systems have been developed as alternatives to standard culture flasks due to
their homogeneous nature, easiness of monitoring and increased cell production. Here we …

As we pursue the means to improve yields to meet growing therapy demands, it is important
to examine the impact of process control on glycosylation patterns to ensure product efficacy …

The aim of the present work was to study the effect of ammonia and lactate on growth,
metabolism, and productivity of BHK cells producing a recombinant fusion protein. Results …