Several immune and immunocompetent cells, including dendritic cells, macrophages,
adipocytes, natural killer cells, T cells, and B cells, are significantly correlated with the …

Transglutaminases (TGs) are multifunctional proteins having enzymatic and scaffolding
functions that participate in regulation of cell fate in a wide range of cellular systems and are …

The LinkedOmics database contains multi-omics data and clinical data for 32 cancer types
and a total of 11 158 patients from The Cancer Genome Atlas (TCGA) project. It is also the …

The ability of breast cancer cells to interconvert between epithelial and mesenchymal states
contributes to their metastatic potential. As opposed to cell autonomous effects, the impact of …

Cancer-associated fibroblasts (CAFs) play crucial roles in enhancing cell survival,
proliferation, invasion, and metastasis. We previously showed that hepatocellular carcinoma …

Stromal immune cells constitute the tumor microenvironment. These immune cell subsets
include myeloid cells, the so-called tumor-associated myeloid cells (TAMCs), which are of …

While meant for wound healing and immunity in response to injury and infection,
inflammatory signaling is usurped by cancerous tumors to promote disease progression …

Introduction Tumor cell interactions with the microenvironment, especially those of bone-
marrow-derived myeloid cells, are important in various aspects of tumor metastasis. Myeloid …

Myeloid-derived suppressor cells (MDSCs) play a pivotal role in promoting tumor growth
and metastasis and can even decrease the efficacy of immunotherapy. In breast cancer …

Abstract Transglutaminase 2 (TG2) is an inducible transamidating acyltransferase that
catalyzes Ca (2+)-dependent protein modifications. In addition to being an enzyme, TG2 …