[PDF][PDF] The potential of secondary metabolites from plants as drugs or leads against protozoan neglected diseases-part II
TJ Schmidt, SA Khalid, ÁJ Romanha, TMA Alves… - 2012 - lavierebelle.org
Infections with protozoan parasites are a major cause of disease and mortality in many
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …
tropical countries of the world. Diseases caused by species of the genera Trypanosoma …
An Ethnopharmacological, Phytochemical and Pharmacological Review on Lignans from Mexican Bursera spp.
MC Marcotullio, M Curini, JX Becerra - Molecules, 2018 - mdpi.com
The genus Bursera belongs to the family Burseraceae and has been used in traditional
Mexican medicine for treating various pathophysiological disorders. The most representative …
Mexican medicine for treating various pathophysiological disorders. The most representative …
In Vitro and In Vivo High-Throughput Assays for the Testing of Anti-Trypanosoma cruzi Compounds
AMC Canavaci, JM Bustamante… - PLoS neglected …, 2010 - journals.plos.org
Background The two available drugs for treatment of T. cruzi infection, nifurtimox and
benznidazole (BZ), have potential toxic side effects and variable efficacy, contributing to their …
benznidazole (BZ), have potential toxic side effects and variable efficacy, contributing to their …
[HTML][HTML] CYP51: A major drug target in the cytochrome P450 superfamily
GI Lepesheva, TY Hargrove, Y Kleshchenko, WD Nes… - Lipids, 2008 - Springer
The cytochrome P540 (CYP) superfamily currently includes about 9,000 proteins forming
more than 800 families. The enzymes catalyze monooxygenation of a vast array of …
more than 800 families. The enzymes catalyze monooxygenation of a vast array of …
Immunomodulatory and Antileishmanial Activity of Phenylpropanoid Dimers Isolated from Nectandra leucantha
TA Costa-Silva, SS Grecco, FS De Sousa… - Journal of natural …, 2015 - ACS Publications
Three phenylpropanoid dimers (1–3) including two new metabolites were isolated from the
extract of the twigs of Nectandra leucantha using antileishmanial bioassay-guided …
extract of the twigs of Nectandra leucantha using antileishmanial bioassay-guided …
Anti‐inflammatory and analgesic activities of the ethanolic extracts from Zanthoxylum riedelianum (Rutaceae) leaves and stem bark
LM Lima, FF Perazzo, JCT Carvalho… - Journal of Pharmacy …, 2007 - Wiley Online Library
We have evaluated the anti‐inflammatory and analgesic properties of the leaves (LCE) and
stem bark (BCE) crude extracts of Zanthoxylum riedelianum (Rutaceae). Different fractions of …
stem bark (BCE) crude extracts of Zanthoxylum riedelianum (Rutaceae). Different fractions of …
In vitro and in vivo antiproliferative and trypanocidal activities of ruthenium NO donors
JJN Silva, AL Osakabe, WR Pavanelli… - British journal of …, 2007 - Wiley Online Library
Background and purpose: Many compounds liberating NO (NO donors) have been used as
therapeutic agents. Here we test two ruthenium nitrosyls, which release NO when activated …
therapeutic agents. Here we test two ruthenium nitrosyls, which release NO when activated …
Advances in Chagas disease drug development: 2009–2010
FS Buckner, N Navabi - Current opinion in infectious diseases, 2010 - journals.lww.com
Advances in Chagas disease drug development: 2009–2010 : Current Opinion in Infectious
Diseases Advances in Chagas disease drug development: 2009–2010 : Current Opinion in …
Diseases Advances in Chagas disease drug development: 2009–2010 : Current Opinion in …
Continuous-flow synthesis of polysubstituted γ-butyrolactones via enzymatic cascade catalysis
L Chu, X Zhang, J Li, X Deng, M Wu, Y Cheng… - Chinese Chemical …, 2024 - Elsevier
Polysubstituted chiral γ-butyrolactones are the core structural units of many natural products
and high value-added flavors and fragrances used in the food and cosmetic industry …
and high value-added flavors and fragrances used in the food and cosmetic industry …
Hinokinin, an emerging bioactive lignan
MC Marcotullio, A Pelosi, M Curini - Molecules, 2014 - mdpi.com
Hinokinin is a lignan isolated from several plant species that has been recently investigated
in order to establish its biological activities. So far, its cytotoxicity, its anti-inflammatory and …
in order to establish its biological activities. So far, its cytotoxicity, its anti-inflammatory and …