The destruction of mucosal barriers, epithelial remodeling, and impaired mucociliary clearance: possible pathogenic mechanisms of Pseudomonas aeruginosa and …

Z Chegini, M Noei, J Hemmati, MR Arabestani… - Cell Communication and …, 2023 - Springer
Chronic rhinosinusitis (CRS) is a pathological condition characterized by persistent
inflammation in the upper respiratory tract and paranasal sinuses. The epithelium serves as …

The role of Staphylococcus aureus enterotoxin B in chronic rhinosinusitis with nasal polyposis

Z Chegini, M Didehdar, A Khoshbayan… - Cell Communication and …, 2022 - Springer
CRS with nasal polyps (CRSwNP) is a multifactorial disease, and various etiological factors
like bacterial superantigens are known to develop this disease. Recent studies reported that …

Ferroptosis is involved in Staphylococcus aureus-induced mastitis through autophagy activation by endoplasmic reticulum stress

L Bao, Y Zhao, S Duan, K Wu, R Shan, Y Liu… - International …, 2024 - Elsevier
Cell death caused by severe Staphylococcus aureus (S. aureus) infection is a fatal threat to
humans and animals. However, whether ferroptosis, an iron-dependent form of cell death, is …

NOD1 and NOD2 activation by diverse stimuli: a possible role for sensing pathogen-induced endoplasmic reticulum stress

SK Kuss-Duerkop, AM Keestra-Gounder - Infection and Immunity, 2020 - Am Soc Microbiol
Prompt recognition of microbes by cells is critical to eliminate invading pathogens. Some cell-
associated pattern recognition receptors (PRRs) recognize and respond to microbial …

[HTML][HTML] Ginsenoside Rb1 protects from Staphylococcus aureus-induced oxidative damage and apoptosis through endoplasmic reticulum-stress and death receptor …

A Shaukat, I Shaukat, SA Rajput, R Shukat… - Ecotoxicology and …, 2021 - Elsevier
Acute lung injury (ALI) is acute uncontrolled inflammation of lung tissue that leads to high
fatality both in human and animals. Staphylococcus aureus (S. aureus) could be an …

Pathophysiology and management of Staphylococcus aureus in nasal polyp disease

Z Xu, J Yan, W Wen, N Zhang… - Expert Review of Clinical …, 2023 - Taylor & Francis
Introduction Staphylococcus aureus (S. aureus) is a common pathogen that frequently
colonizes the sinonasal cavity. Recent studies demonstrated the essential role of …

A nanoscale visual exploration of the pathogenic effects of bacterial extracellular vesicles on host cells

M Kang, MJ Kim, D Jeong, HJ Lim, G Go… - Journal of …, 2024 - Springer
Abstract Background Bacterial extracellular vesicles (EVs) are pivotal mediators of
intercellular communication and influence host cell biology, thereby contributing to the …

Urban particulate matters may affect endoplasmic reticulum stress and tight junction disruption in nasal epithelial cells

SK Park, SH Yeon, MR Choi, SH Choi… - American Journal of …, 2021 - journals.sagepub.com
Background Exposure to airborne urban particulate matter (UPM) has been closely related
to the development and aggravation of respiratory disease, including sinonasal disorders …

Detection of Biofilms in Biopsies from Chronic Rhinosinusitis Patients: In Vitro Biofilm Forming Ability and Antimicrobial Susceptibility Testing in Biofilm Mode of …

M Di Luca, E Navari, S Esin, M Menichini… - … Infectious Diseases and …, 2018 - Springer
Chronic rhinosinusitis (CRS) is the most common illness among chronic disorders that
remains poorly understood from a pathogenic standpoint and has a significant impact on …

Endoplasmic reticulum stress exacerbates inflammation in chronic rhinosinusitis with nasal polyps via the transcription factor XBP1

M Li, Y Xie, K Zhao, K Chen, Y Cao, J Zhang, M Han… - Clinical …, 2021 - Elsevier
Endoplasmic reticulum (ER) stress results in the activation of the unfolded protein response
(UPR), a process that is involved in the pathogenesis of many inflammatory diseases …