Abuse and misuse of pregabalin and gabapentin

KE Evoy, MD Morrison, SR Saklad - Drugs, 2017 - Springer
Background Gabapentinoid (pregabalin and gabapentin) abuse is increasingly being
reported. Objective To assess the extent of gabapentinoid abuse, characteristics of typical …

Gabapentin misuse, abuse and diversion: a systematic review

RV Smith, JR Havens, SL Walsh - Addiction, 2016 - Wiley Online Library
Abstract Background and Aims Since its market release, gabapentin has been presumed to
have no abuse potential and subsequently has been prescribed widely off‐label, despite …

How addictive are gabapentin and pregabalin? A systematic review

U Bonnet, N Scherbaum - European neuropsychopharmacology, 2017 - Elsevier
In the last ten years, gabapentin and pregabalin have been becoming dispensed broadly
and sold on black markets, thereby, exposing millions to potential side-effects. Meanwhile …

Current evidence on abuse and misuse of gabapentinoids

S Hägg, AK Jönsson, J Ahlner - Drug safety, 2020 - Springer
This review summarizes current evidence on the abuse and misuse of the gabapentinoids
pregabalin and gabapentin. Pharmacovigilance studies, register-based studies, surveys …

Gabapentinoid pharmacology in the context of emerging misuse liability

KE Evoy, AM Peckham, JR Covvey… - The Journal of …, 2021 - Wiley Online Library
This article will review the epidemiology and pharmacology of gabapentinoids (gabapentin
and pregabalin) relevant to their emerging misuse potential and provide guidance for …

Gabapentin drug misuse signals: A pharmacovigilance assessment using the FDA adverse event reporting system

R Vickers-Smith, J Sun, RJ Charnigo… - Drug and alcohol …, 2020 - Elsevier
Background Although there have been increasing reports of intentional gabapentin misuse,
epidemiological evidence for the phenomenon is limited. The purpose of this study was to …

Prevalence of gabapentin abuse: comparison with agents with known abuse potential in a commercially insured US population

AM Peckham, KA Fairman, DA Sclar - Clinical Drug Investigation, 2017 - Springer
Background Despite international calls to make gabapentin a controlled substance, studies
of gabapentin use/abuse patterns are limited to small/high-risk samples and adverse event …

Gabapentin controlled substance status

LS Campbell, TN Coomer, GK Jacob… - Journal of the American …, 2021 - Elsevier
Gabapentin is approved to treat postherpetic neuralgia and epilepsy with partial-onset
seizures. The large majority of gabapentin prescribing is off label. Gabapentin may be …

Assessment of community pharmacists' experiences and perceptions on gabapentin abuse in Jordan: a cross-sectional study

R Abu-Farha, L Gharaibeh, KH Alzoubi… - … Policy and Practice, 2024 - Taylor & Francis
Background: Gabapentin is increasingly recognised for its potential for abuse, raising
concerns within healthcare communities. Community pharmacists are on the front lines in …

Trends in prior receipt of prescription opioid or adjuvant analgesics among patients with incident opioid use disorder or opioid-related overdose from 2006 to 2016

YJJ Wei, C Chen, SO Schmidt, WH LoCiganic… - Drug and alcohol …, 2019 - Elsevier
Background With increasing efforts to scrutinize and reduce opioid prescribing, limited data
exist on the recent trend in receipt of prescription pain medications before diagnosis of …