“Radiobiology of Proton Therapy”: Results of an international expert workshop

A Lühr, C von Neubeck, J Pawelke, A Seidlitz… - Radiotherapy and …, 2018 - Elsevier
The physical properties of proton beams offer the potential to reduce toxicity in tumor-
adjacent normal tissues. Toward this end, the number of proton radiotherapy facilities has …

A critical overview of recent stopping power programs for positive ions in solid elements

H Paul, D Sánchez-Parcerisa - … and Methods in Physics Research Section …, 2013 - Elsevier
Several tables exist in the literature containing stopping power data for different targets and
projectile ions. Moreover, Monte Carlo transport codes often incorporate their own …

Prediction and compensation of magnetic beam deflection in MR-integrated proton therapy: a method optimized regarding accuracy, versatility and speed

SM Schellhammer, AL Hoffmann - Physics in Medicine & Biology, 2017 - iopscience.iop.org
The integration of magnetic resonance imaging (MRI) and proton therapy for on-line image-
guidance is expected to reduce dose delivery uncertainties during treatment. Yet, the proton …

The FLUKA Monte Carlo code coupled with the NIRS approach for clinical dose calculations in carbon ion therapy

G Magro, TJ Dahle, S Molinelli, M Ciocca… - Physics in Medicine …, 2017 - iopscience.iop.org
Particle therapy facilities often require Monte Carlo (MC) simulations to overcome intrinsic
limitations of analytical treatment planning systems (TPS) related to the description of the …

Pressure effects on stopping power of alpha particles in argon gas

HM Qadr - Physics of Particles and Nuclei Letters, 2021 - Springer
This paper aims to evaluate the range and stopping power of alpha particles in argon gas at
different pressure of 0 to 1 bar, using the alpha radiation energy. The results show that the …

Towards precise LET measurements based on energy deposition of therapeutic ions in Timepix3 detectors

R Félix-Bautista, Y Hamad… - Physics in medicine …, 2024 - iopscience.iop.org
Objective: There is an increasing interest in calculating and measuring linear energy transfer
(LET) spectra in particle therapy in order to assess their impact in biological terms. As such …

Monte Carlo simulations of a low energy proton beamline for radiobiological experiments

TJ Dahle, AM Rykkelid, CH Stokkevåg, A Mairani… - Acta …, 2017 - Taylor & Francis
Background: In order to determine the relative biological effectiveness (RBE) of protons with
high accuracy, radiobiological experiments with detailed knowledge of the linear energy …

Modeling in vivo relative biological effectiveness in particle therapy for clinically relevant endpoints

A Lühr, C von Neubeck, S Helmbrecht… - Acta …, 2017 - Taylor & Francis
Background: The relative biological effectiveness (RBE) of particle therapy compared to
photon radiotherapy is known to be variable but the exact dependencies are still subject to …

An ion-independent phenomenological relative biological effectiveness (RBE) model for proton therapy

L Tian, C Hahn, A Lühr - Radiotherapy and Oncology, 2022 - Elsevier
Background A relative biological effectiveness (RBE) of 1.1 is used for proton therapy
though clinical evidence of varying RBE was raised. Clinical studies on RBE variability have …

The impact of modeling nuclear fragmentation on delivered dose and radiobiology in ion therapy

A Lühr, DC Hansen, R Teiwes… - Physics in Medicine …, 2012 - iopscience.iop.org
The importance of nuclear interactions for ion therapy arises from the influence of the
particle spectrum on, first, radiobiology and therefore also on treatment planning, second …