Methods for causality assessment of idiosyncratic drug‐induced liver injury

M García‐Cortés, G Matilla‐Cabello… - Liver …, 2024 - Wiley Online Library
The diagnosis of idiosyncratic drug‐induced liver injury (DILI) is a challenging task due to
the lack of specific features or definitive diagnostic tools. A minimum of clinical and …

Intraventricular lavage vs external ventricular drainage for intraventricular hemorrhage: a randomized clinical trial

M Haldrup, M Rasmussen, N Mohamad… - JAMA network …, 2023 - jamanetwork.com
Importance Intraventricular lavage has been proposed as a minimally invasive method to
evacuate intraventricular hemorrhage. There is little evidence to support its use. Objective …

Drug-Induced Movement Disorders

S Pandey, Y Pitakpatapee… - Seminars in …, 2023 - thieme-connect.com
Drug-induced movement disorders (DIMDs) are most commonly associated with typical and
atypical antipsychotics. However, other drugs such as antidepressants, antihistamines …

Causal inference in the medical domain: a survey

X Wu, S Peng, J Li, J Zhang, Q Sun, W Li, Q Qian… - Applied …, 2024 - Springer
Causal inference is considered a crucial topic in the medical field, as it enables the
determination of causal effects for medical treatments through data analysis. However, the …

Analysis of medical malpractice liability disputes related to novel antineoplastic drugs and research on risk prevention and control strategies

J Luo, Z Zheng, R Yu - PLoS One, 2023 - journals.plos.org
Objective To investigate the general characteristics of litigation cases of medical malpractice
liability disputes (MMLDs) related to novel antineoplastic drugs (NADs), the drugs involved …

Post-Infectious Acute Cerebellar Ataxia Treatment, a Case Report and Review of Literature

E Del Giudice, F Mondì, GR Bazzanella, A Marcellino… - Children, 2023 - mdpi.com
Background: infectious mononucleosis is very common during childhood and neurological
manifestations are extremely rare. However, when they occur, an appropriate treatment must …

[HTML][HTML] Clinical aspects of severe cutaneous adverse reactions caused by beta-lactam antibiotics: A study from the Korea SCAR registry

MH Kim, DY Kang, YH Nam, S Kim, JK Lee… - World Allergy …, 2023 - Elsevier
Background Although beta-lactams are 1 of the major causative agents of severe cutaneous
adverse reactions (SCAR), their epidemiology and clinical aspects have been poorly …

Comparison of WHO-UMC and naranjo scales for causality assessment of reported adverse drug reactions

S Pandit, D Soni, B Krishnamurthy… - Journal of Patient …, 2023 - journals.lww.com
Objectives The 2 most commonly used scales worldwide are the World Health Organization–
Uppsala Monitoring Centre (WHO-UMC) and the Naranjo scales. The present study was …

Immune-related generalised oedema–A new category of adverse events with immune checkpoint inhibitors

M Velev, B Baroudjian, R Pruvost, E De Martin… - European Journal of …, 2023 - Elsevier
Background Generalised oedema was occasionally reported associated with immune
checkpoint inhibitors (ICPIs). The purpose of this study is to investigate immune-related …

[HTML][HTML] The WHO Algorithm for Causality Assessment of Adverse Effects Following Immunization with Genetic-Based Anti-COVID-19 Vaccines: Pitfalls and …

P Bellavite, A Donzelli, C Isidoro - Journal of Clinical Medicine, 2024 - mdpi.com
Clarifying and differentiating the causes of diseases is an essential step in any clinical
activity, but it takes on particular relevance and complexity in the case that arise following …