Clozapine treatment is associated with higher prescription rate of antipsychotic monotherapy and lower prescription rate of other concomitant psychotropics: a real …

S Ochi, H Tagata, N Hasegawa… - International Journal …, 2022 - academic.oup.com
Background Although clozapine is effective for treatment-resistant schizophrenia (TRS), the
rate of clozapine prescription is still low. Whereas antipsychotic monotherapy is …

Effect of education regarding treatment guidelines for schizophrenia and depression on the treatment behavior of psychiatrists: A multicenter study

N Hasegawa, Y Yasuda… - Psychiatry and …, 2023 - Wiley Online Library
Aim This study aims to examine the real‐world effectiveness of education regarding clinical
guidelines for psychiatric disorders using 'the Effectiveness of guidelines for dissemination …

Hypnotic medication use among inpatients with schizophrenia and major depressive disorder: results of a nationwide study

R Furihata, R Otsuki, N Hasegawa, T Tsuboi, S Numata… - Sleep Medicine, 2022 - Elsevier
Study objectives To investigate the proportion of inpatients with schizophrenia and major
depressive disorder prescribed hypnotic medication, and the association between such …

Overcoming the barriers to identifying and managing treatment-resistant schizophrenia and to improving access to clozapine: A narrative review and recommendation …

O Agid, B Crespo-Facorro, A de Bartolomeis… - European …, 2024 - Elsevier
Clozapine is the only approved antipsychotic for treatment-resistant schizophrenia (TRS).
Although a large body of evidence supports its efficacy and favorable risk-benefit ratio in …

The characteristics of patients receiving psychotropic pro re nata medication at discharge for the treatment of schizophrenia and major depressive disorder: a …

K Ichihashi, Y Kyou, N Hasegawa… - Asian Journal of …, 2022 - Elsevier
Background Although several guidelines indicate that daily pharmacotherapy is an
important part of the treatment of schizophrenia and major depressive disorder, there are …

[HTML][HTML] Characteristics of the treatments for each severity of major depressive disorder: A real-world multi-site study

H Muraoka, F Kodaka, N Hasegawa… - Asian Journal of …, 2022 - Elsevier
Purpose In the treatment guidelines for major depressive disorder (MDD), the recommended
treatment differs based on the severity. However, the type of treatment provided based on …

[HTML][HTML] Prescription of anticholinergic drugs in patients with schizophrenia: analysis of antipsychotic prescription patterns and hospital characteristics

H Hori, N Yasui-Furukori, N Hasegawa, J Iga… - Frontiers in …, 2022 - frontiersin.org
In several clinical guidelines for schizophrenia, long-term use of anticholinergic drugs is not
recommended. We investigated the characteristics of the use of anticholinergics in patients …

Prescribing trends for the same patients with schizophrenia over 20 years

N Yasui-Furukori, Y Kawamata, T Sasaki… - Neuropsychiatric …, 2023 - Taylor & Francis
Background Recent pharmacoepidemiology data show an increase in the proportion of
patients receiving second-generation antipsychotic (SGA) monotherapy, but no studies have …

Effects of electroconvulsive therapy on the use of anxiolytics and sleep medications: a propensity score‐matched analysis

T Tsuboi, Y Takaesu, N Hasegawa… - Psychiatry and …, 2023 - Wiley Online Library
Aim We investigated the association of electroconvulsive therapy (ECT) with anxiolytic and
sleep medication use in patients with major depressive disorder (MDD) and schizophrenia …

[HTML][HTML] Change of prescription for patients with schizophrenia or major depressive disorder during admission: real-world prescribing surveys from the effectiveness of …

N Hashimoto, N Yasui-Furukori, N Hasegawa… - BMC psychiatry, 2023 - Springer
Background Polypharmacy of additional psychotropics alongside the main treatment drug
(antipsychotics in schizophrenia and antidepressants in major depressive disorder) is …