A systematic review of the protective effects of silymarin/silibinin against doxorubicin-induced cardiotoxicity

M Singh, MM Kadhim, A Turki Jalil, SK Oudah… - Cancer Cell …, 2023 - Springer
Purpose Although doxorubicin chemotherapy is commonly applied for treating different
malignant tumors, cardiotoxicity induced by this chemotherapeutic agent restricts its clinical …

Environmental contaminants and male infertility: Effects and mechanisms

V Selvaraju, S Baskaran, A Agarwal, R Henkel - Andrologia, 2021 - Wiley Online Library
The escalating prevalence of male infertility and decreasing trend in sperm quality have
been correlated with rapid industrialisation and the associated discharge of an excess of …

Silymarin: a review on paving the way towards promising pharmacological agent

MN Akhtar, R Saeed, F Saeed, A Asghar… - … Journal of Food …, 2023 - Taylor & Francis
Advancements in the field of research and development have paved toward the use of
herbal agents to cure and control health maladies. Milk thistle (Silybum marianum L.) is one …

[HTML][HTML] The interplay of arsenic, silymarin, and NF-ĸB pathway in male reproductive toxicity: A review

AG Mukherjee, AV Gopalakrishnan - Ecotoxicology and Environmental …, 2023 - Elsevier
Arsenic toxicity is one of the most trending reasons for several malfunctions, particularly
reproductive toxicity. The exact mechanism of arsenic poisoning is a big question mark …

Redox mechanisms of environmental toxicants on male reproductive function

T Hussain, E Metwally, G Murtaza… - Frontiers in Cell and …, 2024 - frontiersin.org
Humans and wildlife, including domesticated animals, are exposed to a myriad of
environmental contaminants that are derived from various human activities, including …

Ameliorative effects of rutin and rutin-loaded chitosan nanoparticles on testicular oxidative stress and histological damage induced by cyclophosphamide in male rats

DA AbdElrazek, NH Hassan, MA Ibrahim… - Food and Chemical …, 2024 - Elsevier
Cyclophosphamide (CP) is broadly used to kill various tumor cells; however, its repeated
uses have been reported to cause reproductive dysfunction and infertility. Natural flavonoid …

N‐nitrosamines induced infertility and hepatotoxicity in male rabbits

SA Sheweita, YY El Banna, M Balbaa… - Environmental …, 2017 - Wiley Online Library
N‐nitrosamines are widely spread environmental pollutants of well‐known toxicity and
carcinogenicity in various animal species. These compounds are metabolically activated by …

Urinary polycyclic aromatic hydrocarbon metabolites and human semen quality in China

P Yang, YX Wang, YJ Chen, L Sun, J Li… - … science & technology, 2017 - ACS Publications
Toxicological studies have demonstrated that polycyclic aromatic hydrocarbons (PAHs)
exposure impairs male reproductive health. However, the epidemiological evidence is …

Effect of prenatal exposure to Benzo [a] pyrene on ovarian toxicity and reproductive dysfunction: Protective effect of atorvastatin in the embryonic period

Z Rahmani, A Karimpour Malekshah… - Environmental …, 2021 - Wiley Online Library
As an environmental contaminant, Benzo [a] pyrene (B [a] P; BaP) disrupts the antioxidant
signaling and thus leads to the induction of oxidative stress and the damage of DNA in the …

Combined effect of polystyrene nanoplastic and di-n-butyl phthalate on testicular health of male Swiss albino mice: analysis of sperm-related parameters and potential …

K Sharma, A Sharma, P Bhatnagar - Environmental Science and Pollution …, 2024 - Springer
Plastics, especially polystyrene nanoplastic particles (PSNPs), are known for their durability
and absorption properties, allowing them to interact with environmental pollutants such as di …