Cyclophosphamide (CP) is an important anticancer drug which belongs to the class of
alkylating agent. Cyclophosphamide is mostly used in bone marrow transplantation …

Natural antioxidants have received tremendous attention over the last 3 decades. At the
same time, the attitude to free radicals is slowly changing, and their signalling role in …

Fertility preservation is an emerging discipline, which is of substantial clinical value in the
care of young patients with cancer. Chemotherapy and radiation may induce ovarian …

Cyclophosphamide is an alkylating antineoplastic agent, and it is one of the most successful
drugs with wide arrays of clinical activity. It has been in use for several types of cancer …

Background: Cyclophosphamide (CP)(Cytoxan or Endoxan) is an efficient anti-tumor agent,
widely used for the treatment of various neoplastic diseases. The study aimed to investigate …

Radiotherapy is a well-known cause of premature ovarian failure (POF). Therefore, we
investigated the molecular influence of genistein (GEN) on the ovarian reserve of rats …

The objective of this study is to evaluate the possible protective effects of selenium (Se)
against cyclophosphamide (CP)-induced acute cardiotoxicity in rats. A total of 42 male …

In this study, the protective effects of Quercetin (Q) and Rutin in 5-fluorouracil (5-FU)-induced
cardiotoxicity in rats were investigated and used eighty-piece Sprague Dawley male rats …

Aims Although chemotherapeutic agents have highly beneficial effects against cancer, they
disturb the body's normal homeostasis. One of the critical side effects of chemotherapeutic …

Lung injury is a significant complication associated with cholestasis/cirrhosis. This problem
significantly increases the risk of cirrhosis-related morbidity and mortality. Hence, finding …