Compared with traditional 2D adherent cell culture, 3D spheroidal cell aggregates, or
spheroids, are regarded as more physiological, and this technique has been exploited in the …

Significance: Poor wound healing remains a significant health issue for a large number of
patients in the United States. The physiologic response to local wound hypoxia plays a …

Mesenchymal stem cells (MSCs) are primary candidates in cell therapy and tissue
engineering and are being tested in clinical trials for a wide range of diseases. Originally …

Orthobiologics continue to gain popularity in many areas of medical science, especially in
the field of regenerative medicine. Platelet-rich plasma derivatives are orthobiologic tools of …

Mesenchymal stem cells (MSC) have been considered the promising candidates for the
regenerative and personalized medicine due to their self-renewal potential, multilineage …

Mesenchymal stem cells (MSCs) have been demonstrated as promising cell sources for
tissue regeneration due to their capability of self-regeneration, differentiation, and …

Since the discovery of scarless fetal skin wound healing, research in the field has expanded
significantly with the hopes of advancing the finding to adult human patients. There are …

One of the most importantly involved pathways in cancer development is fatty-acid signaling
pathway. Synthesized lipids as energetic sources are consumed by cancer cells for …

Over the past few years, mesenchymal stem (or stromal) cells (MSCs) have garnered
enormous interest due to their therapeutic value especially for their multilineage …

Background Bone fracture initiates a series of cellular and molecular events including the
expression of hypoxia-inducible factor (HIF)-1. HIF-1 is known to facilitate recruitment and …