Subpopulations of extracellular vesicles and their therapeutic potential
Extracellular vesicles (EVs), such as exosomes and microvesicles, have over the last 10–15
years been recognized to convey key messages in the molecular communication between …
years been recognized to convey key messages in the molecular communication between …
Poly (ADP-ribose) polymerase-1 cleavage during apoptosis: an update
C Soldani, AI Scovassi - Apoptosis, 2002 - Springer
Poly (ADP-ribosylation) is a post-translational modification of proteins playing a crucial role
in many processes, including DNA repair and cell death. The best known poly (ADP …
in many processes, including DNA repair and cell death. The best known poly (ADP …
The extracellular release of HMGB1 during apoptotic cell death
CW Bell, W Jiang, CF Reich III… - American Journal of …, 2006 - journals.physiology.org
High mobility group box 1 protein (HMGB1) is a non-histone nuclear protein with dual
function. Inside the cell, HMGB1 binds DNA and regulates transcription, whereas outside the …
function. Inside the cell, HMGB1 binds DNA and regulates transcription, whereas outside the …
Extracellular vesicles arising from apoptosis: Forms, functions, and applications
CD Gregory, MP Rimmer - The Journal of Pathology, 2023 - Wiley Online Library
Extracellular vesicles (EVs) are lipid bilayer‐enclosed subcellular bodies produced by most,
if not all cells. Research over the last two decades has recognised the importance of EVs in …
if not all cells. Research over the last two decades has recognised the importance of EVs in …
Characterization of amplifiable, circulating RNA in plasma and its potential as a tool for cancer diagnostics
T El-Hefnawy, S Raja, L Kelly, WL Bigbee… - Clinical …, 2004 - academic.oup.com
Background: Several recent reports have described the detection of circulating, cancer-
related RNA molecules in serum or plasma from cancer patients, but little is known about the …
related RNA molecules in serum or plasma from cancer patients, but little is known about the …
Nonresonant confocal Raman imaging of DNA and protein distribution in apoptotic cells
N Uzunbajakava, A Lenferink, Y Kraan, E Volokhina… - Biophysical journal, 2003 - cell.com
Nonresonant confocal Raman imaging has been used to map the DNA and the protein
distributions in individual single human cells. The images are obtained on an improved …
distributions in individual single human cells. The images are obtained on an improved …
The apoptosis cascade—morphological and immunohistochemical methods for its visualization
B Huppertz, HG Frank, P Kaufmann - Anatomy and embryology, 1999 - Springer
Apoptosis is involved in morphogenesis of embryonic tissues as well as in homeostasis of
adult organs and tissues. It is the main process by which organs maintain cell mass and at …
adult organs and tissues. It is the main process by which organs maintain cell mass and at …
Segregation of RNA and separate packaging of DNA and RNA in apoptotic bodies during apoptosis
HD Halicka, E Bedner, Z Darzynkiewicz - Experimental cell research, 2000 - Elsevier
Apoptosis is characterized by a complex and remarkably ordered choreography of events
consisting of the preparatory and execution steps that all culminate in disposal of the cell …
consisting of the preparatory and execution steps that all culminate in disposal of the cell …
The role of apoptosis in vascular disease
MM Kockx, MWM Knaapen - The Journal of pathology, 2000 - Wiley Online Library
Normal arteries are characterized by a low turnover of endothelial (EC) and smooth muscle
cells (SMC). Different mechanisms protect the EC and SMC against apoptosis in the normal …
cells (SMC). Different mechanisms protect the EC and SMC against apoptosis in the normal …
Poly (ADP-ribose) polymerase cleavage during apoptosis: when and where?
C Soldani, MC Lazzè, MG Bottone, G Tognon… - Experimental cell …, 2001 - Elsevier
Poly (ADP-ribose) polymerase-1 (PARP-1) plays the active role of “nick sensor” during DNA
repair and apoptosis, when it synthesizes ADP-ribose from NAD+ in the presence of DNA …
repair and apoptosis, when it synthesizes ADP-ribose from NAD+ in the presence of DNA …