PV interneurons: critical regulators of E/I balance for prefrontal cortex-dependent behavior and psychiatric disorders

BR Ferguson, WJ Gao - Frontiers in neural circuits, 2018 - frontiersin.org
Elucidating the prefrontal cortical microcircuit has been challenging, given its role in multiple
complex behaviors, including working memory, cognitive flexibility, attention, social …

Glutamate hypothesis in schizophrenia

Y Uno, JT Coyle - Psychiatry and clinical neurosciences, 2019 - Wiley Online Library
Schizophrenia is a chronic and severe psychiatric disorder that has profound impact on an
individual's life and on society. Thus, developing more effective therapeutic interventions is …

Role of cholesterol and sphingolipids in brain development and neurological diseases

G Hussain, J Wang, A Rasul, H Anwar, A Imran… - Lipids in health and …, 2019 - Springer
Brain is a vital organ of the human body which performs very important functions such as
analysis, processing, coordination, and execution of electrical signals. For this purpose, it …

Hippocampal GABAergic inhibitory interneurons

KA Pelkey, R Chittajallu, MT Craig… - Physiological …, 2017 - journals.physiology.org
In the hippocampus GABAergic local circuit inhibitory interneurons represent only~ 10–15%
of the total neuronal population; however, their remarkable anatomical and physiological …

Norepinephrine ignites local hotspots of neuronal excitation: How arousal amplifies selectivity in perception and memory

M Mather, D Clewett, M Sakaki… - Behavioral and Brain …, 2016 - cambridge.org
Emotional arousal enhances perception and memory of high-priority information but impairs
processing of other information. Here, we propose that, under arousal, local glutamate levels …

[引用][C] Consciousness and the Brain: Deciphering How the Brain Codes Our Thoughts

S Dehaene - 2014 - books.google.com
WINNER OF THE 2014 BRAIN PRIZE From the acclaimed author of Reading in the Brain
and How We Learn, a breathtaking look at the new science that can track consciousness …

The origin of NMDA receptor hypofunction in schizophrenia

K Nakazawa, K Sapkota - Pharmacology & therapeutics, 2020 - Elsevier
Abstract N-methyl-d-aspartate (NMDA) receptor (NMDAR) hypofunction plays a key role in
pathophysiology of schizophrenia. Since NMDAR hypofunction has also been reported in …

Glutamate and gamma-aminobutyric acid systems in the pathophysiology of major depression and antidepressant response to ketamine

MS Lener, MJ Niciu, ED Ballard, M Park, LT Park… - Biological …, 2017 - Elsevier
In patients with major depressive disorder or bipolar disorder, abnormalities in excitatory
and/or inhibitory neurotransmission and neuronal plasticity may lead to aberrant functional …

EEG and MEG: relevance to neuroscience

FL da Silva - Neuron, 2013 - cell.com
To understand dynamic cognitive processes, the high time resolution of EEG/MEG is
invaluable. EEG/MEG signals can play an important role in providing measures of functional …

Prefrontal parvalbumin neurons in control of attention

H Kim, S Ährlund-Richter, X Wang, K Deisseroth… - Cell, 2016 - cell.com
While signatures of attention have been extensively studied in sensory systems, the neural
sources and computations responsible for top-down control of attention are largely …