Heart failure with preserved ejection fraction in the elderly: scope of the problem

B Upadhya, GE Taffet, CP Cheng… - Journal of molecular and …, 2015 - Elsevier
Heart failure with preserved ejection fraction (HFpEF) is the most common form of heart
failure (HF) in older adults, particularly women, and is increasing in prevalence as the …

Heart failure with preserved ejection fraction in older adults

B Upadhya, DW Kitzman - Tresch and Aronow's Cardiovascular …, 2019 - taylorfrancis.com
Heart failure (HF) with preserved left ventricular (LV) ejection fraction (HFpEF) is uncommon
in younger persons, but highly prevalent in older adults, particularly women over age 80 …

Effects of supervised exercise and dietary nitrate in older adults with controlled hypertension and/or heart failure with preserved ejection fraction

HA Shaltout, J Eggebeen, AP Marsh, PH Brubaker… - Nitric Oxide, 2017 - Elsevier
Aerobic exercise training is an effective therapy to improve peak aerobic power (peak VO 2)
in individuals with hypertension (HTN, AHA/ACC class A) and heart failure patients with …

Association is not causation: treatment effects cannot be estimated from observational data in heart failure

CJ Rush, RT Campbell, PS Jhund… - European heart …, 2018 - academic.oup.com
Aims Treatment 'effects' are often inferred from non-randomized and observational studies.
These studies have inherent biases and limitations, which may make therapeutic inferences …

Heart failure with preserved ejection fraction in the elderly: basic mechanisms and clinical considerations

K Gharagozloo, M Mehdizadeh, G Heckman… - Canadian Journal of …, 2024 - Elsevier
Heart failure (HF) with preserved ejection fraction (HFpEF) refers to a clinical condition in
which the signs of HF, such as pulmonary congestion, peripheral edema and increased …

Beta-blockers in older patients with heart failure and preserved ejection fraction: class, dosage, and outcomes

K Patel, GC Fonarow, OJ Ekundayo, IB Aban… - International journal of …, 2014 - Elsevier
Background We examined the clinical effectiveness of beta-blockers considered evidenced-
based to heart failure and reduced ejection fraction (HFrEF) and their recommended target …

Sudden death in heart failure with preserved ejection fraction and beyond: an elusive target

AS Manolis, AA Manolis, TA Manolis, H Melita - Heart failure reviews, 2019 - Springer
Heart failure (HF) with preserved ejection fraction (HFpEF) represents half of HF patients,
who are more likely older, women, and hypertensive. Mortality rates in HFpEF are higher …

Calcium channel blockers and outcomes in older patients with heart failure and preserved ejection fraction

K Patel, GC Fonarow, M Ahmed, C Morgan… - Circulation: Heart …, 2014 - Am Heart Assoc
Background—Little is known about associations of calcium channel blockers (CCBs) with
outcomes in patients with heart failure and preserved ejection fraction (EF). Methods and …

Therapy for heart failure with preserved ejection fraction: current status, unique challenges, and future directions

B Upadhya, MJ Haykowsky, DW Kitzman - Heart failure reviews, 2018 - Springer
Heart failure (HF) with preserved ejection fraction (HFpEF) is the most common form of HF.
Among elderly women, HFpEF comprises more than 80% of incident HF cases. Adverse …

Beta-blocker use and 30-day all-cause readmission in Medicare beneficiaries with systolic heart failure

V Bhatia, NS Bajaj, K Sanam, T Hashim… - The American journal of …, 2015 - Elsevier
Background Beta-blockers improve outcomes in patients with systolic heart failure. However,
it is unknown whether their initial negative inotropic effect may increase 30-day all-cause …