Analyzing and Modifying Sialic Acid at the Glycan End: Systematic Review of Methods and Functional Outcomes

Y We, L Zheng, Y Chen, J Jiao, J Jiao, Y Guo - TrAC Trends in Analytical …, 2024 - Elsevier
Sialic acid, a nine-carbon monosaccharide at the termini of glycan chains, is intricately
linked to tumor progression and disease, necessitating highly sensitive analytical methods …

Methylome–proteome integration after late‐life voluntary exercise training reveals regulation and target information for improved skeletal muscle health

TL Chambers, A Dimet‐Wiley, AR Keeble… - The Journal of …, 2024 - Wiley Online Library
Exercise is a potent stimulus for combatting skeletal muscle ageing. To study the effects of
exercise on muscle in a preclinical setting, we developed a combined endurance …

In-depth analysis of lymph node metastasis-related sialylated protein profiling and their clinical and biological significance in colorectal cancer using mass …

Y Shao, M Yu, L Zhang, L Zhou, X Yan, B Feng… - Scientific Reports, 2024 - nature.com
Colorectal cancer (CRC) lymph node metastasis (LNM) is a crucial factor affecting the
prognosis and treatment outcomes of CRC patients. It has been confirmed that altered …

[HTML][HTML] Severe kidney dysfunction in sialidosis mice reveals an essential role for neuraminidase 1 in reabsorption

I Kho, EP Demina, X Pan, I Londono, CW Cairo… - JCI insight, 2023 - ncbi.nlm.nih.gov
Sialidosis is an ultra-rare multisystemic lysosomal disease caused by mutations in the
neuraminidase 1 (NEU1) gene. The severe type II form of the disease manifests with a …

Serum proteomic biomarker investigation of vascular depression using data-independent acquisition: a pilot study

L Lan, S Peng, R Zhang, H He, Y Yang, B Xi… - Frontiers in Aging …, 2024 - frontiersin.org
Background Vascular depression (VaD) is a depressive disorder closely associated with
cerebrovascular disease and vascular risk factors. It remains underestimated owing to …

Regulation of Reabsorption Process in Kidney by Neuraminidase 1: Implications in Nephrosialidosis

I Kho - 2023 - search.proquest.com
Sialidosis is an ultra-rare multisystemic lysosomal disease caused by mutations in the gene
encoding for Neuraminidase 1 (NEU1) that cleaves terminal sialic acid residues from glycan …

Electrophilicity Modulation for Sub‐ppm Visualization and Discrimination of EDA

H Zhao, Y Liu, G Li, D Lei, Y Du, Y Li, H Tang… - Advanced …, 2024 - Wiley Online Library
Precise and timely recognition of hazardous chemical substances is of great significance for
safeguarding human health, ecological environment, public security, etc., especially crucial …