Alzheimer's Disease (AD) is a progressive neurodegenerative disorder that effects 50 million
people worldwide. In this review, AD pathology and the development of novel therapeutic …

The objective of this study is to recognize the potential traditional Chinese medicinal
compound by virtual screening and docking analysis for the amyloid-beta disaggregation …

Diabetes mellitus (DM) is a serious, long-term disease when the pancreas doesn't make
enough insulin or when the body can't use the insulin it makes well. Type 2 Diabetes …

Ultrasound and microbubbles are used for many medical applications nowadays. Scanning
ultrasound can remove amyloid-β (Aβ) aggregates in the mouse brain and restores memory …

The present study aimed to identify the prospective inhibitors of MurD, a cytoplasmic enzyme
that catalyzes the addition of d-glutamate to the UDP-N-acetylmuramoyl-l-alanine nucleotide …

Amyloid-β (Aβ) oligomers are known as the most toxic form of Aβ peptides, and they are a
major contributor to Alzheimer's disease. Therefore, developing antagonist screening …

The present study attempts to identify the novel inhibitors of shikimate dehydrogenase (SD),
the enzyme that catalyzes the fourth reaction in the shikimate pathway, through virtual …

Listeriolysine-O (LLO) is a 50KDa protein responsible for Listeria monocytogenes
pathogenicity. The structure of LLO (PDB ID: 4CDB) with domains D1 to D4 is known …

This study aimed to identify compounds that are capable of inhibiting polyphosphate kinase
(PPK), the protein that shares a similar pathway with the target of isoniazid (INH) in the …

Alzheimer's disease (AD) represents an enormous global health burden in terms of human
suffering and economic cost. AD management requires a shift from the prevailing paradigm …