Cardiomyocyte differentiation of mesenchymal stem cells from bone marrow: new regulators and its implications
X Guo, Y Bai, L Zhang, B Zhang, N Zagidullin… - Stem cell research & …, 2018 - Springer
In the past years, cardiac mortality has decreased, but cardiac diseases are still responsible
for millions of deaths every year worldwide. Bone-marrow mesenchymal stem cells (BMSCs) …
for millions of deaths every year worldwide. Bone-marrow mesenchymal stem cells (BMSCs) …
Vascular development
MW Majesky - Arteriosclerosis, thrombosis, and vascular biology, 2018 - Am Heart Assoc
The vascular system forms as a branching network of endothelial cells that acquire identity
as arterial, venous, hemogenic, or lymphatic. Endothelial specification depends on gene …
as arterial, venous, hemogenic, or lymphatic. Endothelial specification depends on gene …
MYB–A regulatory factor in hematopoiesis
X Wang, N Angelis, SL Thein - Gene, 2018 - Elsevier
MYB is a transcription factor which was identified in birds as a viral oncogene (v-MYB). Its
cellular counterpart was subsequently isolated as c-MYB which has three functional …
cellular counterpart was subsequently isolated as c-MYB which has three functional …
Smooth muscle heterogeneity and plasticity in health and aortic aneurysmal disease
Y Hu, Z Cai, B He - International Journal of Molecular Sciences, 2023 - mdpi.com
Vascular smooth muscle cells (VSMCs) are the predominant cell type in the medial layer of
the aorta, which plays a critical role in the maintenance of aortic wall integrity. VSMCs have …
the aorta, which plays a critical role in the maintenance of aortic wall integrity. VSMCs have …
Navigating the landscape: Prospects and hurdles in targeting vascular smooth muscle cells for atherosclerosis diagnosis and therapy
J He, Y Gao, C Yang, Y Guo, L Liu, S Lu… - Journal of Controlled …, 2024 - Elsevier
Vascular smooth muscle cells (VSMCs) have emerged as pivotal contributors throughout all
phases of atherosclerotic plaque development, effectively dispelling prior underestimations …
phases of atherosclerotic plaque development, effectively dispelling prior underestimations …
O-Linked β-N-acetylglucosamine modification of A20 enhances the inhibition of NF-κB (nuclear factor-κB) activation and elicits vascular protection after acute …
D Yao, L Xu, O Xu, R Li, M Chen, H Shen… - … , and vascular biology, 2018 - Am Heart Assoc
Objective—Recently, we have demonstrated that acute glucosamine-induced augmentation
of protein O-linked β-N-acetylglucosamine (O-GlcNAc) levels inhibits inflammation in …
of protein O-linked β-N-acetylglucosamine (O-GlcNAc) levels inhibits inflammation in …
B-cell deficiency lowers blood pressure in mice
LS Dingwell, EA Shikatani, R Besla, AS Levy… - …, 2019 - Am Heart Assoc
The proto-oncogene c-myb (and corresponding nuclear transcription factor, c-Myb)
regulates the proliferation and differentiation of hematologic and vascular smooth muscle …
regulates the proliferation and differentiation of hematologic and vascular smooth muscle …
Vascular smooth muscle cells
MW Majesky - Arteriosclerosis, thrombosis, and vascular biology, 2016 - Am Heart Assoc
Majesky Vascular Smooth Muscle Cells e83 adherens junction structures composed of
hybrid nanotracks of N-cadherin and cadherin-11. Blocking either N-cadherin or cadherin …
hybrid nanotracks of N-cadherin and cadherin-11. Blocking either N-cadherin or cadherin …
miR579-3p is an inhibitory modulator of neointimal hyperplasia and transcription factors c-MYB and KLF4
Neointimal hyperplasia (IH) is a common vascular pathology that typically manifests in in-
stent restenosis and bypass vein graft failure. Smooth muscle cell (SMC) phenotypic …
stent restenosis and bypass vein graft failure. Smooth muscle cell (SMC) phenotypic …
Macrophage-derived MMP-8 determines smooth muscle cell differentiation from adventitia stem/progenitor cells and promotes neointima hyperplasia
F Yang, Q Chen, M Yang, EM Maguire… - Cardiovascular …, 2020 - academic.oup.com
Aims Emerging evidence has suggested that adventitia stem/progenitor cells (AdSPCs)
migrate into the intima of arteries in response to injury, where they differentiate towards …
migrate into the intima of arteries in response to injury, where they differentiate towards …