Cartilage is one of the very few naturally occurring avascular tissues where lack of
angiogenesis is the guiding principle for its structure and function. This has attracted …

A variety of pathogenic mechanisms have been described in the formation, maturation, and
rupture of brain arteriovenous malformations (bAVMs). While the understanding of bAVMs …

Rationale: Brain arteriovenous malformations (AVMs) are abnormal tangles of vessels
where arteries and veins directly connect without intervening capillary nets, increasing the …

Abstract We investigated (1) EphrinB2 and EphB4 receptor expression in cerebral AVMs,(2)
the impact of an altered EphrinB2: EphB4 ratio on brain endothelial cell function and (3) …

The neurovascular unit is composed of endothelial cells, vascular smooth muscle cells,
pericytes, astrocytes and neurons. Through tightly regulated multi-directional cell signaling …

Background and Purpose—Cerebral arteriovenous malformation (AVM) is a vascular
disease that disrupts normal blood flow and leads to serious neurological impairment or …

Inhibitor of DNA-binding/differentiation (Id) proteins, a family of helix-loop-helix (HLH)
proteins that includes four members of Id1 to Id4 in mammalian cells, are critical for …

Abstract Background Brain arteriovenous malformations (AVMs) are rare, potentially
devastating cerebrovascular lesions that can occur in both children and adults. AVMs are …

Background Cerebral arteriovenous malformation (AVM) is a vascular disease exhibiting
abnormal blood vessel morphology and function. miR‐18a ameliorates the abnormal …

Brain arteriovenous malformations (bAVMs) are relatively rare, although their potential for
secondary intracranial haemorrhage (ICH) makes their diagnosis and management …