Breast cancer is the most commonly diagnosed cancer in women. Metastasis is the primary
cause of mortality for breast cancer patients. Multiple mechanisms underlie breast cancer …

Breast cancer has grown to be the second leading cause of cancer-related deaths in
women. Only a few treatment options are available for breast cancer due to the widespread …

The blood–tumor barrier (BTB) contributes to poor therapeutic efficacy by limiting drug
uptake; therefore, elevating BTB permeability is essential for glioma treatment. Here, we …

In the present study, we inspected the role of naringenin-loaded nanostructured lipid carriers
(NLCs) in the induction of apoptosis in (HT-29) colon cancer cell in co-administration with …

Background Induction of immunogenic cell death (ICD) is considered a promising strategy
for cancer immunotherapy. Stattic is an inhibitor of STAT3, which is found constitutively …

Monolayer cultures, the less standard three-dimensional (3D) culturing systems, and
xenografts are the main tools used in current basic and drug development studies of cancer …

Adjuvant-aided combination chemotherapy is one of the most effective ways of cancer
treatment by overcoming the multidrug resistance (MDR) and reducing the side-effects of …

Introduction Glutathione reductase (GSR) provides reduced glutathione (GSH) to maintain
redox homeostasis. Inhibition of GSR disrupts this balance, resulting in cell damage, which …

Drug delivery-based nanoparticle has been developing as a widespread innovation in
cancer treatment protocols. Here, we investigated the role of Kaempferol (KAE) loaded in …

Polymeric micelles produced from amphiphilic copolymers, are considered promising drug
delivery platforms. Because of their ability to co-deliver hydrophilic (Dox) and hydrophobic …