Phospholipase D: a lipid centric review

GM Jenkins, MA Frohman - Cellular and Molecular Life Sciences CMLS, 2005 - Springer
Phospholipase D (PLD) hydrolyzes the phosphodiester bond of the glycerolipid
phosphatidylcholine, resulting in the production of phosphatidic acid and free choline …

Phospholipase d

M McDermott, MJO Wakelam… - Biochemistry and Cell …, 2004 - cdnsciencepub.com
La phospholipase D catalyse l'hydrolyse de la liaison phosphodiester des
glycérophospholipides, ce qui produit l'acide phosphatidique et un alcool polaire. Des …

Phospholipase D2, a distinct phospholipase D isoform with novel regulatory properties that provokes cytoskeletal reorganization

WC Colley, TC Sung, R Roll, J Jenco, SM Hammond… - Current Biology, 1997 - cell.com
Background: Activation of phospholipase D (PLD) is an important but poorly understood
component of receptor-mediated signal transduction responses and regulated secretion. We …

Phospholipase D: a downstream effector of ARF in granulocytes

S Cockcroft, GMH Thomas, A Fensome, B Geny… - Science, 1994 - science.org
Activation of the phospholipase D (PLD) pathway is a widespread response when cells are
activated by agonists that bind receptors on the cell surface. A 16-kD cytosolic component …

[HTML][HTML] Mutagenesis of phospholipase D defines a superfamily including a trans‐Golgi viral protein required for poxvirus pathogenicity

TC Sung, RL Roper, Y Zhang, SA Rudge… - The EMBO …, 1997 - embopress.org
Phospholipase D (PLD) genes are members of a superfamily that is defined by several
highly conserved motifs. PLD in mammals has been proposed to play a role in membrane …

Regulation of eukaryotic phosphatidylinositol-specific phospholipase C and phospholipase D

WD Singer, HA Brown… - Annual review of …, 1997 - annualreviews.org
This review focuses on two phospholipase activities involved in eukaryotic signal
transduction. The action of the phosphatidylinositol-specific phospholipase C enzymes …

Phospholipase D: enzymology, mechanisms of regulation, and function

JH Exton - Physiological reviews, 1997 - journals.physiology.org
Phospholipase D exists in various forms that differ in their regulation but predominantly
hydrolyze phosphatidylcholine. The Ca (2+)-dependent isozymes of protein kinase C …

[HTML][HTML] Phospholipase D1: a key factor for the exocytotic machinery in neuroendocrine cells

N Vitale, AS Caumont, S Chasserot-Golaz, G Du… - The EMBO …, 2001 - embopress.org
Phospholipase D (PLD) has been proposed to mediate cytoskeletal remodeling and
vesicular trafficking along the secretory pathway. We recently described the activation of an …

Structure and Function of ARF Proteins: Activators of Cholera Toxin and Critical Components of Intracellular Vesicular Transport Processes (∗)

J Moss, M Vaughan - Journal of Biological Chemistry, 1995 - ASBMB
During the 1980s, several cellular factors that enhanced cholera toxin-catalyzed ADP-
ribosylation of Gsa or activation of adenylyl cyclase were described. Kahn and Gilman (1) …

Evidence that phospholipase D mediates ADP ribosylation factor-dependent formation of Golgi coated vesicles.

NT Ktistakis, HA Brown, MG Waters… - The Journal of cell …, 1996 - rupress.org
Formation of coatomer-coated vesicles from Golgi-enriched membranes requires the
activation of a small GTP-binding protein, ADP ribosylation factor (ARF). ARF is also an …