Ovarian carcinomas: five distinct diseases with different origins, genetic alterations, and clinicopathological features

J Prat - Virchows Archiv, 2012 - Springer
Malignant epithelial tumors (carcinomas) are the most common ovarian cancers and also
the most lethal gynecological malignancies. Based on histopathology and molecular genetic …

The rise of a novel classification system for endometrial carcinoma; integration of molecular subclasses

J McAlpine, A Leon‐Castillo… - The Journal of pathology, 2018 - Wiley Online Library
Endometrial cancer is a clinically heterogeneous disease and it is becoming increasingly
clear that this heterogeneity may be a function of the diversity of the underlying molecular …

Invasive epithelial ovarian cancer survival by histotype and disease stage

LC Peres, KL Cushing-Haugen, M Köbel… - JNCI: Journal of the …, 2019 - academic.oup.com
Background The understanding of ovarian cancer pathogenesis has recently shifted to
recognize distinct changes in how ovarian cancer histotypes are defined. Using the 2014 …

International Endocervical Adenocarcinoma Criteria and Classification (IECC): a new pathogenetic classification for invasive adenocarcinomas of the endocervix

S Stolnicu, I Barsan, L Hoang, P Patel… - The American journal …, 2018 - journals.lww.com
We sought to classify endocervical adenocarcinomas (ECAs) based on morphologic
features linked to etiology (ie, human papillomavirus [HPV] infection), unlike the World …

Evaluating cell lines as tumour models by comparison of genomic profiles

S Domcke, R Sinha, DA Levine, C Sander… - Nature …, 2013 - nature.com
Cancer cell lines are frequently used as in vitro tumour models. Recent molecular profiles of
hundreds of cell lines from The Cancer Cell Line Encyclopedia and thousands of tumour …

[HTML][HTML] Association between endometriosis and risk of histological subtypes of ovarian cancer: a pooled analysis of case–control studies

CL Pearce, C Templeman, MA Rossing, A Lee… - The lancet …, 2012 - thelancet.com
Background Endometriosis is a risk factor for epithelial ovarian cancer; however, whether
this risk extends to all invasive histological subtypes or borderline tumours is not clear. We …

Malignant extracellular vesicles carrying MMP1 mRNA facilitate peritoneal dissemination in ovarian cancer

A Yokoi, Y Yoshioka, Y Yamamoto, M Ishikawa… - Nature …, 2017 - nature.com
Advanced ovarian cancers are highly metastatic due to frequent peritoneal dissemination,
resulting in dismal prognosis. Here we report the functions of cancer-derived extracellular …

Hormone-receptor expression and ovarian cancer survival: an Ovarian Tumor Tissue Analysis consortium study

W Sieh, M Köbel, TA Longacre, DD Bowtell… - The lancet …, 2013 - thelancet.com
Background Few biomarkers of ovarian cancer prognosis have been established, partly
because subtype-specific associations might be obscured in studies combining all …

Ovarian low-grade and high-grade serous carcinoma: pathogenesis, clinicopathologic and molecular biologic features, and diagnostic problems

R Vang, IM Shih, RJ Kurman - Advances in anatomic pathology, 2009 - journals.lww.com
Ovarian serous carcinomas have been graded using various systems. Recently, a 2-tier
system in which tumors are subdivided into low grade and high grade has been proposed …

Ovarian carcinoma subtypes are different diseases: implications for biomarker studies

M Köbel, SE Kalloger, N Boyd, S McKinney… - PLoS …, 2008 - journals.plos.org
Background Although it has long been appreciated that ovarian carcinoma subtypes
(serous, clear cell, endometrioid, and mucinous) are associated with different natural …